INT69318

Context Info Confidence 0.35 First Reported 1997 Last Reported 1997 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.09 Pain Relevance 0.21

small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2) Golgi apparatus (ST3GAL4) enzyme binding (PTGS2) protein complex (PTGS2) cytoplasm (PTGS2)

ST3GAL4 (Homo sapiens) PTGS2 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 1 92.72 cytokine 3 91.28 Inflammation 1 33.76

Disease Link Frequency Relevance Heat INFLAMMATION 2 92.48

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

SK&F 86002 dose-dependently inhibited this STZ-induced expression of PGHS-2 protein, which correlated with a decrease in prostaglandin E2 and thromboxane A2 production.

STZ Positive_regulation (induced) of Gene_expression (expression) of PGHS-2 protein

1) Confidence 0.35 Published 1997 Journal J. Immunol. Section Abstract Doc Link 9144511 Disease Relevance 0.09 Pain Relevance 0.21

General Comments

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