INT70468

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Context Info
Confidence 0.40
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTG1) nucleolus (MTG1) nucleus (MTG1)
plasma membrane (HTR1B) cytoplasm (HTR1B) signal transducer activity (HTR1B)
HTR1B (Homo sapiens)
MTG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Sumatriptan 4 95.00 High High
agonist 14 93.44 High High
Serotonin 2 90.32 High High
antagonist 4 79.36 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GR127935 (10 microM) exerted little effect on [35S]GTP gamma S binding via h5-HT1B receptors (10% stimulation), but potently (pA2: 9.11) antagonized h5-HT1B receptor-stimulated [35S]GTP gamma S binding.
5-HT1B Binding (binding) of GTP
1) Confidence 0.40 Published 1997 Journal Neuropharmacology Section Abstract Doc Link 9225275 Disease Relevance 0 Pain Relevance 0.47
Compounds either stimulated or inhibited [35S]GTP gamma S binding to a membrane preparation containing either h5-HT1B or h5-HT1D receptors.
5-HT1B Binding (binding) of GTP
2) Confidence 0.40 Published 1997 Journal Neuropharmacology Section Abstract Doc Link 9225275 Disease Relevance 0 Pain Relevance 0.09

General Comments

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