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Context Info
Confidence 0.07
First Reported 1997
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.56
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Il4i1) lysosome (Il4i1)
Il4i1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 33 99.80 Very High Very High Very High
Patient controlled alalgesia 21 98.24 Very High Very High Very High
antagonist 7 97.64 Very High Very High Very High
Morphine 15 95.92 Very High Very High Very High
Serotonin 1 90.16 High High
Neurotransmitter 2 86.56 High High
Enkephalin 5 86.16 High High
tolerance 42 63.60 Quite High
Neuropeptide 1 59.12 Quite High
Opioid 8 53.24 Quite High
Disease Link Frequency Relevance Heat
Appetite Loss 5 100.00 Very High Very High Very High
Pain 49 99.80 Very High Very High Very High
Body Weight 1 68.12 Quite High
Post Operative Pain 18 50.00 Quite Low
Breast Cancer 1 39.84 Quite Low
Disease 2 39.24 Quite Low
Obesity 3 39.20 Quite Low
INFLAMMATION 9 28.20 Quite Low
Sepsis 10 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Endotoxin- and interleukin-1-induced hypophagia are not affected by adrenergic, dopaminergic, histaminergic, or muscarinic antagonists.
Neg (not) Regulation (affected) of interleukin-1-induced associated with appetite loss and antagonist
1) Confidence 0.07 Published 1999 Journal Pharmacol. Biochem. Behav. Section Title Doc Link 10462192 Disease Relevance 0.32 Pain Relevance 0.25
The median VAS scores during the first 3 PODs revealed that pain was well-controlled for the population as a whole (Fig 1).
Regulation (controlled) of Fig 1 associated with pain
2) Confidence 0.05 Published 2010 Journal Eplasty Section Body Doc Link PMC2941188 Disease Relevance 0.24 Pain Relevance 1.01
Moreover, the ease of hydrolysis of this bioactive peptide, coupled with the revelation of the other enzymic steps involving the fragments generated, may provide important clues as to the possible role of the oligopeptidases (and L-amino acid oxidase) in the venom.
Spec (possible) Regulation (role) of L-amino acid oxidase
3) Confidence 0.03 Published 1997 Journal Toxicon Section Abstract Doc Link 9248009 Disease Relevance 0 Pain Relevance 0.34
Differential Ub of the same molecule, leading to distinct signaling outcomes, was first coined “ubiquitin editing” by Lam and colleagues to describe quantitative changes in ubiquitination (32) and was subsequently adopted by Newton and colleagues to describe the regulation of IL-1-induced IRAK-1 (33).
Regulation (regulation) of IL-1-induced
4) Confidence 0.01 Published 2010 Journal mBio Section Body Doc Link PMC2962435 Disease Relevance 0 Pain Relevance 0.03

General Comments

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