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Context Info
Confidence 0.42
First Reported 1997
Last Reported 2011
Negated 6
Speculated 4
Reported most in Body
Documents 144
Total Number 149
Disease Relevance 180.34
Pain Relevance 18.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lung 17
respiratory 8
heart 3
spinal 2
parenchyma 2
COPD (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 408 100.00 Very High Very High Very High
palliative 377 100.00 Very High Very High Very High
qutenza 7 100.00 Very High Very High Very High
Inflammatory response 129 99.98 Very High Very High Very High
Inflammatory marker 21 99.96 Very High Very High Very High
Inflammation 1952 99.92 Very High Very High Very High
corticosteroid 333 99.84 Very High Very High Very High
depression 215 99.60 Very High Very High Very High
Inflammatory mediators 147 99.54 Very High Very High Very High
Opioid 275 99.52 Very High Very High Very High
Disease Link Frequency Relevance Heat
Pulmonary Disease 8514 100.00 Very High Very High Very High
Disease 1813 100.00 Very High Very High Very High
Dyspnea 1390 100.00 Very High Very High Very High
Nicotine Addiction 1213 100.00 Very High Very High Very High
Myocardial Infarction 746 100.00 Very High Very High Very High
Obesity 632 100.00 Very High Very High Very High
Chronic Obstructive Pulmonary Disease 421 100.00 Very High Very High Very High
Apnoea 286 100.00 Very High Very High Very High
Infection 264 100.00 Very High Very High Very High
Respiratory Failure 251 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Advanced COPD is associated with considerable psychological morbidity.
COPD Binding (associated) of associated with pulmonary disease
1) Confidence 0.42 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2528206 Disease Relevance 1.40 Pain Relevance 0.94
Additionally, we need to recognize COPD as a systematic disease, and consider intensive care in postoperative period.
COPD Binding (recognize) of associated with pulmonary disease and disease
2) Confidence 0.41 Published 2010 Journal Masui Section Abstract Doc Link 20662279 Disease Relevance 1.06 Pain Relevance 0.09
The results provide further evidence that COPD is associated with weight loss, while there is no materially increased risk for ulcer or GORD associated with COPD.
COPD Neg (no) Binding (associated) of associated with weight loss, pulmonary disease, ulcers and gastroesophageal reflux disease
3) Confidence 0.41 Published 2010 Journal COPD Section Abstract Doc Link 20486815 Disease Relevance 2.71 Pain Relevance 0
COPD is associated with enormous healthcare costs.
COPD Binding (associated) of associated with pulmonary disease
4) Confidence 0.41 Published 2009 Journal Drugs Aging Section Abstract Doc Link 19761275 Disease Relevance 1.45 Pain Relevance 0.08
We examined the association between COPD and 30-day mortality following bleeding and perforation of a peptic ulcer.
COPD Spec (examined) Binding (association) of associated with pulmonary disease, ulcers and hemorrhage
5) Confidence 0.41 Published 2008 Journal Chest Section Abstract Doc Link 18339786 Disease Relevance 1.02 Pain Relevance 0.09
Females have been reported to have a worse prognosis of COPD and higher measures of adiposity.2223 BMI, used in our study, does not differentiate between obese men and muscular men, which may skew the results in the male cohort.24 Moreover, the discovered association of COPD and obesity with increased length of stay and hospital cost in the cervical variant of spine surgery may not be true for hospital systems that have different structure and payment arrangements from the American healthcare system.
COPD Binding (association) of in spine associated with pulmonary disease and obesity
6) Confidence 0.40 Published 2010 Journal Indian Journal of Orthopaedics Section Body Doc Link PMC2947730 Disease Relevance 1.78 Pain Relevance 0.04
It is important to recognize that COPD, in most cases, is associated with significant, albeit never complete, reversibility [87-89] at one time or another.
COPD Neg (never) Binding (recognize) of associated with pulmonary disease
7) Confidence 0.39 Published 2010 Journal Respir Res Section Body Doc Link PMC2991288 Disease Relevance 1.55 Pain Relevance 0.03
As previously mentioned, COPD is associated with an abnormal inflammatory response of the lungs to noxious particles or gases.
COPD Binding (associated) of in lungs associated with inflammatory response and pulmonary disease
8) Confidence 0.38 Published 2009 Journal Respir Res Section Body Doc Link PMC2678087 Disease Relevance 1.37 Pain Relevance 0.09
COPD is associated with an abnormal inflammatory response of the lungs to noxious particles or gases.
COPD Binding (associated) of in lungs associated with inflammatory response and pulmonary disease
9) Confidence 0.38 Published 2009 Journal Respir Res Section Body Doc Link PMC2678087 Disease Relevance 0.93 Pain Relevance 0.05
Much of the morbidity and mortality associated with COPD are due to acute exacerbations.
COPD Binding (associated) of associated with pulmonary disease
10) Confidence 0.37 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2692119 Disease Relevance 1.60 Pain Relevance 0
Therefore there is potential for significant virus–bacteria interaction in COPD but little data is available regarding this.
COPD Binding (interaction) of associated with pulmonary disease
11) Confidence 0.37 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2692119 Disease Relevance 2.19 Pain Relevance 0
However more recent studies using modern diagnostic methods such as polymerase chain reaction (PCR) have achieved much higher viral detection rates and the association of virus infections with COPD is much higher than previously suspected.
COPD Binding (association) of associated with pulmonary disease and infection
12) Confidence 0.37 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2692119 Disease Relevance 1.79 Pain Relevance 0
Thus, our results may indicate the similar inflammatory response in smokers and ex-smokers with COPD, which is associated not only with smoking, but also with systemic inflammation.
COPD Binding (associated) of associated with inflammatory response, pulmonary disease, nicotine addiction and inflammation
13) Confidence 0.36 Published 2007 Journal Respir Res Section Body Doc Link PMC2200652 Disease Relevance 2.48 Pain Relevance 0.36
At this time, only a few clinical variables or inflammatory mediators have been shown to be associated with COPD exacerbations and their related morbidity and mortality.
COPD Binding (associated) of associated with inflammatory mediators and pulmonary disease
14) Confidence 0.35 Published 2006 Journal Respir Res Section Body Doc Link PMC1481583 Disease Relevance 0.82 Pain Relevance 0.05
Eosinophilic inflammation is generally not associated with COPD.
COPD Binding (associated) of associated with rhinitis, pulmonary disease and inflammation
15) Confidence 0.35 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2629961 Disease Relevance 2.04 Pain Relevance 0.41
OSAS patients may also present sustained pulmonary hypertension (Sanner et al 1997; Sajkov et al 1999; Bady et al 2000), and the risk increases considerably if it is associated with COPD, obesity or both (Bradley 1992; Laks et al 1995; Chaouat et al 1996).
COPD Binding (associated) of associated with obesity, chronic obstructive pulmonary disease, hypertension and obstructive sleep apnea
16) Confidence 0.35 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650593 Disease Relevance 1.82 Pain Relevance 0
Doherty et al (2000) investigated the cough reflex sensitivity to capsaicin in COPD and asthma compared with healthy volunteers.
COPD Binding (capsaicin) of associated with asthma, pulmonary disease, qutenza and cough
17) Confidence 0.33 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2707150 Disease Relevance 1.81 Pain Relevance 0.25
Another important barrier to end of life care is that misconceptions about both COPD and palliative care abound.
COPD Binding (abound) of associated with pulmonary disease and palliative
18) Confidence 0.32 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2528206 Disease Relevance 0.97 Pain Relevance 0.22
Barriers to good end of life care in COPD
COPD Binding (Barriers) of associated with pulmonary disease
19) Confidence 0.32 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2528206 Disease Relevance 1.17 Pain Relevance 0.10
There are many factors contributing to the poor quality of life suffered by patient with COPD.
COPD Binding (patient) of associated with pulmonary disease
20) Confidence 0.32 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2528206 Disease Relevance 0.97 Pain Relevance 0.05

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