INT72516

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Context Info
Confidence 0.44
First Reported 1997
Last Reported 2004
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.40
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Drd1a) plasma membrane (Drd1a) nucleus (Drd1a)
intracellular (Drd1a) signal transducer activity (Drd1a)
Drd1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 6 100.00 Very High Very High Very High
Nucleus accumbens 5 98.60 Very High Very High Very High
antagonist 1 87.92 High High
drug abuse 1 77.20 Quite High
Enkephalin 3 75.68 Quite High
Disease Link Frequency Relevance Heat
Stress 8 75.00 Quite High
Generalized Anxiety Disorder 2 73.60 Quite High
Depression 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No changes in dopamine D1 receptor binding were observed in any group.
Neg (No) Regulation (changes) of dopamine D1 receptor Binding (binding) of associated with dopamine
1) Confidence 0.44 Published 2004 Journal Neuroscience Section Abstract Doc Link 14980394 Disease Relevance 0.26 Pain Relevance 0.52
In contrast to the uniform reduction in D2-receptor binding, fluphenazine altered D1-receptor binding in a region-dependent manner.
Regulation (altered) of D1-receptor Binding (binding) of
2) Confidence 0.18 Published 1997 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9387879 Disease Relevance 0.14 Pain Relevance 0.12

General Comments

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