INT72616

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Context Info
Confidence 0.41
First Reported 1997
Last Reported 2002
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.97
Pain Relevance 2.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Tcf3) nucleus (Tcf3) DNA binding (Tcf3)
protein complex (Tcf3) transcription factor binding (Tcf3) cytoplasm (Tcf3)
Anatomy Link Frequency
caudate putamen 1
Tcf3 (Mus musculus)
Pain Link Frequency Relevance Heat
Dynorphin 9 100.00 Very High Very High Very High
Kappa opioid receptor 4 100.00 Very High Very High Very High
Central grey 1 100.00 Very High Very High Very High
Serotonin 2 99.36 Very High Very High Very High
Nerve growth factor 11 98.40 Very High Very High Very High
Nucleus accumbens 2 98.36 Very High Very High Very High
Opioid 3 93.72 High High
Inflammation 6 92.36 High High
qutenza 2 91.36 High High
Ventral tegmentum 1 90.48 High High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 100.00 Very High Very High Very High
INFLAMMATION 4 92.36 High High
Targeted Disruption 1 82.44 Quite High
Hypersensitivity 6 75.00 Quite High
Sprains And Strains 1 67.72 Quite High
Asthma 1 60.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the DBA/2 mice presented a higher content of kappa-opioid receptors in the periaqueductal gray and dynorphin A 1-13 and dynorphin A 1-8 in the caudate putamen.
Negative_regulation (presented) of A 1 in caudate putamen associated with dynorphin, kappa opioid receptor and central grey
1) Confidence 0.41 Published 1997 Journal Alcohol. Clin. Exp. Res. Section Abstract Doc Link 9394118 Disease Relevance 0.17 Pain Relevance 1.25
These effects were paralleled by increased serotonin levels in the airways, whereas immunoglobulin E levels remained unaffected.
Neg (unaffected) Negative_regulation (unaffected) of immunoglobulin E associated with serotonin
2) Confidence 0.05 Published 2002 Journal Am. J. Respir. Crit. Care Med. Section Abstract Doc Link 12231491 Disease Relevance 0.80 Pain Relevance 0.79

General Comments

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