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Context Info
Confidence 0.68
First Reported 1997
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 12
Total Number 13
Disease Relevance 8.18
Pain Relevance 2.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Icam1) cell adhesion (Icam1) plasma membrane (Icam1)
Anatomy Link Frequency
CD86 1
C3A 1
Icam1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 40 99.50 Very High Very High Very High
ischemia 26 99.02 Very High Very High Very High
anesthesia 12 95.28 Very High Very High Very High
cva 7 90.68 High High
cytokine 31 86.68 High High
Inflammation 123 86.28 High High
alcohol 6 85.60 High High
tolerance 4 82.48 Quite High
Percutaneous transluminal coronary angioplasty 27 78.88 Quite High
Inflammatory mediators 8 53.28 Quite High
Disease Link Frequency Relevance Heat
Adhesions 87 100.00 Very High Very High Very High
Cv General 3 Under Development 23 99.50 Very High Very High Very High
Coronary Artery Disease 15 99.02 Very High Very High Very High
Myocardial Infarction 16 98.56 Very High Very High Very High
Hypertension 57 98.28 Very High Very High Very High
Diabetes Mellitus 63 97.72 Very High Very High Very High
Brain Injury 83 93.36 High High
Emergencies 3 91.68 High High
Angina 22 90.08 High High
Disorder Of Lipid Metabolism 54 89.36 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum sTM and ICAM-1 levels were also significantly increased after reperfusion (sTM: 3.3+/-0.8 to 5.1+/-1.7 FU/ml, p=0.0001; ICAM-1: 271.9+/-86.3 to 515.0+/-157.8 FU/ml, p=0.0001).
Localization (levels) of ICAM-1
1) Confidence 0.68 Published 2008 Journal Int. J. Mol. Med. Section Abstract Doc Link 18097619 Disease Relevance 0.40 Pain Relevance 0.20
As shown in Figure 4(a), few ICAM-1-immunostained cerebral
Localization (few) of ICAM-1
2) Confidence 0.68 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2375967 Disease Relevance 0.80 Pain Relevance 0.09
Both soluble ICAM-1 and VCAM-1 appeared to be trapped in the coronary circulation at baseline and released into the coronary circulation following coronary spasm and reperfusion in the patients.


Localization (released) of ICAM-1
3) Confidence 0.57 Published 1997 Journal Cardiovasc. Res. Section Body Doc Link 9415270 Disease Relevance 0 Pain Relevance 0
Measurement of COX-2 and ICAM-1
Localization (Measurement) of ICAM
4) Confidence 0.52 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2880261 Disease Relevance 0.38 Pain Relevance 0.14
and the appearance of COX-2 and ICAM were statistically not different in each group.


Localization (appearance) of ICAM
5) Confidence 0.49 Published 2010 Journal Yonsei Medical Journal Section Abstract Doc Link PMC2880261 Disease Relevance 0.61 Pain Relevance 0.03
The apparently "negative" results on ICAM-1, VCAM-1 and RANTES should not be misinterpreted to exclude a role of these factors.
Neg (not) Localization (misinterpreted) of ICAM-1
6) Confidence 0.42 Published 2005 Journal BMC Nephrol Section Body Doc Link PMC1175090 Disease Relevance 1.24 Pain Relevance 0.03
Increased release of the soluble form of the adhesion molecules L-selectin and ICAM-1 but not E-selectin during attacks of angina pectoris.
Localization (release) of ICAM-1 associated with angina and adhesions
7) Confidence 0.18 Published 1998 Journal Heart Vessels Section Title Doc Link 10442400 Disease Relevance 1.30 Pain Relevance 0.50
The purpose of our study was to verify whether myocardial ischemia occurring during angina episodes results in the release of the soluble adhesion molecules, L-selectin, E-selectin, and intracellular adhesion molecule-1 (ICAM-1), into the circulation.
Localization (release) of ICAM-1 associated with angina, coronary artery disease, ischemia and adhesions
8) Confidence 0.18 Published 1998 Journal Heart Vessels Section Abstract Doc Link 10442400 Disease Relevance 1.52 Pain Relevance 0.59
Both soluble ICAM-1 and PECAM-1 have been reported released into the circulation following reperfusion after acute myocardial ischemia, resulting in a transient increase within the first hours after reperfusion [28, 32].
Localization (released) of ICAM-1 associated with coronary artery disease and ischemia
9) Confidence 0.18 Published 2001 Journal Crit Care Section Body Doc Link PMC31578 Disease Relevance 0.68 Pain Relevance 0.25
Protein levels were visualized by incubation with the following antibodies: bcl-2, caspase-3, ICAM-1, HO-1, NF-?
Localization (visualized) of ICAM-1
10) Confidence 0.18 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2873601 Disease Relevance 0.12 Pain Relevance 0.08
Protein levels of sICAM released by C3A cells increased in a dose-dependent manner (Figure 4(a)).
Localization (released) of sICAM in C3A
11) Confidence 0.15 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2817554 Disease Relevance 0.49 Pain Relevance 0.11
Leptin maximally increased sICAM release by approximately 1.5-fold at a dose of 62.5?
Localization (release) of sICAM
12) Confidence 0.15 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2817554 Disease Relevance 0.47 Pain Relevance 0.11
It was recently found that LSEC constitutively express all molecules necessary for antigen presentation: CD54, CD80, CD86, MHC class I and II, and CD40, and can function as antigen-presenting cells for CD4+ and CD8+ T cells [67,68].
Localization (presentation) of CD54 in CD86
13) Confidence 0.09 Published 2004 Journal Comp Hepatol Section Body Doc Link PMC2409441 Disease Relevance 0.16 Pain Relevance 0.13

General Comments

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