INT72992

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Context Info
Confidence 0.50
First Reported 1998
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.19
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein targeting (Gphn) plasma membrane (Gphn) cytoskeleton (Gphn)
intracellular (Gphn) protein binding, bridging (Gphn) cytoplasm (Gphn)
Anatomy Link Frequency
nucleus 1
Gphn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 62 99.68 Very High Very High Very High
gABA 22 94.36 High High
Spinal cord 1 94.20 High High
Cannabinoid 5 93.48 High High
tetrodotoxin 3 92.28 High High
agonist 7 79.20 Quite High
Central nervous system 1 76.68 Quite High
antagonist 2 62.36 Quite High
hyperexcitability 1 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 122 96.64 Very High Very High Very High
Stress 42 50.00 Quite Low
Post-traumatic Stress Disorder 16 5.00 Very Low Very Low Very Low
Shock 7 5.00 Very Low Very Low Very Low
Cognitive Disorder 6 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Phobia 3 5.00 Very Low Very Low Very Low
Overactive Bladder 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Affective Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The abundance of GlyR subunits and gephyrin fell sharply in the axotomized facial nucleus.
Transcription (abundance) of gephyrin in nucleus
1) Confidence 0.50 Published 2005 Journal Eur. J. Neurosci. Section Abstract Doc Link 15733085 Disease Relevance 0 Pain Relevance 0.16
Chhatwal et al. [100] showed that gephyrin mRNA and protein levels in the BLA significantly
Transcription (levels) of gephyrin associated with amygdala
2) Confidence 0.26 Published 2007 Journal Neural Plasticity Section Body Doc Link PMC1838961 Disease Relevance 0.19 Pain Relevance 0.55
Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis revealed that the glycine receptor alpha1, alpha2, beta subunits and gephyrin mRNAs were expressed at comparable levels in strychnine-treated and untreated cultures.
Transcription (expressed) of gephyrin
3) Confidence 0.20 Published 1998 Journal J. Cell. Sci. Section Abstract Doc Link 9427682 Disease Relevance 0 Pain Relevance 0.09

General Comments

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