INT74033

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Context Info
Confidence 0.08
First Reported 1998
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.87
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ighg1) extracellular region (IGHG3)
IGHG3 (Homo sapiens)
Ighg1 (Mus musculus)
Pain Link Frequency Relevance Heat
abdominal pain 1 62.00 Quite High
neuralgia 4 50.00 Quite Low
corticosteroid 1 5.00 Very Low Very Low Very Low
pruritus 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cyst 2 88.84 High High
Immunization 7 88.56 High High
Malaria 35 82.80 Quite High
Giardiasis 3 75.00 Quite High
Genital Herpes Simplex 2 67.40 Quite High
Vomiting 2 63.60 Quite High
Abdominal Pain 1 62.00 Quite High
Diarrhoea 1 61.36 Quite High
Infection 5 50.00 Quite Low
Neuralgia 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared with all control subjects, low levels of total IgG1 (odds ratio [OR], 4.9 [95% confidence interval {CI}, 2.0-12.5]; P=.001) and IgG3 (OR 3.6 [95% CI 1.7-7.8]; P=.001), but not of anti-HSV-2 antibodies, were associated with recurrences.
IgG3 Binding (associated) of IgG1
1) Confidence 0.08 Published 2006 Journal J. Infect. Dis. Section Body Doc Link 16897653 Disease Relevance 0.07 Pain Relevance 0
Most importantly all individuals receiving the vaccine developed specific immune responses and the antibodies produced were almost exclusively in the two classes IgG1 and IgG3 which can bind Fc?
IgG3 Binding (bind) of IgG1
2) Confidence 0.03 Published 2009 Journal Malar J Section Body Doc Link PMC2720982 Disease Relevance 0.23 Pain Relevance 0
The antigen recognition by anti-parasite IgM, IgA, IgG1, and IgG3 of symptomatic and asymptomatic individuals, determined by immunoblotting, was heterogeneous and revealed only minor differences in the response of the two groups.
IgG3 Spec (determined) Binding (recognition) of IgG1
3) Confidence 0.03 Published 1998 Journal Am. J. Trop. Med. Hyg. Section Abstract Doc Link 9502609 Disease Relevance 0.58 Pain Relevance 0.06

General Comments

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