INT74156

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Context Info
Confidence 0.49
First Reported 1998
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.54
Pain Relevance 2.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il12b) cytoplasm (Il12b)
Il12b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 23 100.00 Very High Very High Very High
Inflammatory response 7 97.72 Very High Very High Very High
Neuritis 8 96.60 Very High Very High Very High
Sciatic nerve 2 94.92 High High
Inflammation 55 94.64 High High
cytokine 88 94.00 High High
Peripheral nervous system 2 75.00 Quite High
Demyelination 2 75.00 Quite High
Inflammatory stimuli 7 35.44 Quite Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 2 99.92 Very High Very High Very High
INFLAMMATION 65 97.72 Very High Very High Very High
Experimental Autoimmune Neuritis 8 96.60 Very High Very High Very High
Wallerian Degeneration 6 96.28 Very High Very High Very High
Demyelinating Disease 2 75.00 Quite High
Granuloma 11 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 10 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Bladder Cancer 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL12p40-mRNA was upregulated later than IFNgamma-mRNA in the late acute phase from days 15 to 21.
Positive_regulation (upregulated) of IL12
1) Confidence 0.49 Published 1998 Journal J. Neurosci. Res. Section Abstract Doc Link 9514202 Disease Relevance 0.63 Pain Relevance 0.64
Significant levels of mRNA for IFNgamma could be found at days 4 and 7, whereas IL12p40-mRNA showed a biphasic induction.
Positive_regulation (induction) of IL12
2) Confidence 0.45 Published 1998 Journal J. Neurosci. Res. Section Abstract Doc Link 9514202 Disease Relevance 0.54 Pain Relevance 0.68
, IL-2, IL-3, IL-4, IL-6, IL-10, IL-12p70, IL-17, GM-CSF, KC, and RANTES induction discriminate between the effects of BCG relative to the inflammatory responses obtained with LPS and TNF-?
Positive_regulation (induction) of IL-12 associated with chemokine and inflammatory response
3) Confidence 0.20 Published 2007 Journal BMC Immunol Section Body Doc Link PMC1891101 Disease Relevance 0.37 Pain Relevance 0.72

General Comments

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