INT76015

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Context Info
Confidence 0.14
First Reported 1998
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.04
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DCSTAMP)
DCSTAMP (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 1 90.56 High High
cytokine 10 89.68 High High
tetrodotoxin 2 87.40 High High
cINOD 6 81.92 Quite High
Inflammation 2 78.40 Quite High
COX-2 inhibitor 1 58.60 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Necrosis 2 98.98 Very High Very High Very High
Cancer 2 98.80 Very High Very High Very High
Diarrhoea 4 80.72 Quite High
Infection 2 79.92 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 79.52 Quite High
Inflammatory Bowel Disease 6 79.16 Quite High
INFLAMMATION 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unlike IL-1beta, NS-398 and Cig did not cause NF-kappaB (p65) nuclear translocation, nor did they further enhance IL-1beta-induced NF-kappaB translocation, but they stimulated PPARgamma translocation.
Localization (translocation) of IL-1beta-induced
1) Confidence 0.14 Published 2003 Journal J. Immunol. Section Abstract Doc Link 12517972 Disease Relevance 0.07 Pain Relevance 0.36
An ISC maximum of 2.5+/-0.3 micromol. h-1.cm-2 was reached at 20 ng/ml within 43+/-4 min. 22Na+ and 36Cl- fluxes were not altered and residual flux increased by 2.4+/-1.0 micromol.h-1.cm-2 indicating that the IL-1beta-induced ISC is based on electrogenic bicarbonate secretion.
Localization (secretion) of IL-1beta-induced
2) Confidence 0.13 Published 1998 Journal Cytokine Section Abstract Doc Link 9632533 Disease Relevance 0.51 Pain Relevance 0.20
At half maximum effective concentrations an additive action of tumour necrosis factor alpha (TNF-alpha) could be demonstrated on IL-1beta-induced secretion.
Localization (secretion) of IL-1beta-induced associated with necrosis and cancer
3) Confidence 0.13 Published 1998 Journal Cytokine Section Abstract Doc Link 9632533 Disease Relevance 0.46 Pain Relevance 0.21

General Comments

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