INT76633

Context Info Confidence 0.04 First Reported 1997 Last Reported 2010 Negated 1 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.79 Pain Relevance 1.61

cell proliferation (BCAT1) cytosol (BCAT1) small molecule metabolic process (BCAT1) cellular nitrogen compound metabolic process (BCAT1) cytoplasm (BCAT1)

BCAT1 (Homo sapiens)

Pain Link Frequency Relevance Heat gABA 6 100.00 Glutamate 2 100.00 Gabapentin 14 99.98 Neurotransmitter 1 80.24 Pain 2 77.12 Hyperalgesia 1 73.68

Disease Link Frequency Relevance Heat Generalized Anxiety Disorder 1 100.00 Partial Seizures 1 81.48 Convulsion 1 77.64 Pain 2 77.12 Hyperalgesia 1 73.68 Death 1 70.88 Neurodegenerative Disease 1 67.20 Motor Neuron Diseases 1 65.12 Stress Fractures 12 62.64 Anxiety Disorder 1 58.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Ethnicity did not affect BCT-induced changes in PTH.

Neg (not) Regulation (affect) of BCT

1) Confidence 0.04 Published 2010 Journal J Int Soc Sports Nutr Section Abstract Doc Link PMC3017021 Disease Relevance 0.12 Pain Relevance 0

In vitro, gabapentin modulates the action of the GABA synthetic enzyme, glutamic acid decarboxylase (GAD) and the glutamate synthesizing enzyme, branched-chain amino acid transaminase.

Regulation (modulates) of branched-chain amino acid transaminase associated with glutamate, gaba, generalized anxiety disorder and gabapentin

2) Confidence 0.04 Published 1997 Journal Rev. Neurol. (Paris) Section Abstract Doc Link 9686247 Disease Relevance 0.67 Pain Relevance 1.61

General Comments

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