INT77353

Context Info Confidence 0.65 First Reported 1998 Last Reported 1998 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.84

intracellular (Gnai1) GTPase activity (Gnai1) cytoplasm (Gnai1) signal transducer activity (Gnai1) signal transduction (Gnai1) nucleus (Gnai1)

Gnai1 (Mus musculus)

Pain Link Frequency Relevance Heat Potency 3 99.90 MU agonist 1 99.74 nociceptor 1 98.66 Intracerebroventricular 1 97.88 Opioid 3 85.68 Enkephalin 1 84.68 Morphine 2 81.60 Analgesic 2 81.24 analgesia 1 48.12

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The effects of antisense to Gialpha2 on opioid agonist potency and Gialpha2 protein and mRNA abundance in the mouse.

Transcription (abundance) of Gialpha2 associated with mu agonist, nociceptor and potency

1) Confidence 0.65 Published 1998 Journal Brain Res. Mol. Brain Res. Section Title Doc Link 9729412 Disease Relevance 0 Pain Relevance 0.84

General Comments

This test has worked.