INT77354

Context Info Confidence 0.34 First Reported 1998 Last Reported 1998 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.96

intracellular (Gnai1) GTPase activity (Gnai1) cytoplasm (Gnai1) signal transducer activity (Gnai1) signal transduction (Gnai1) nucleus (Gnai1)

Gnai1 (Mus musculus)

Pain Link Frequency Relevance Heat Potency 3 95.24 Analgesic 2 94.92 Morphine 2 94.44 Opioid 3 78.16 analgesia 1 76.96 Enkephalin 1 76.40 MU agonist 1 75.00 Intracerebroventricular 1 63.72 nociceptor 1 25.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Using a quantitative immunoblotting procedure, antisense treatment was shown to decrease striatal Gialpha2 protein 48 h after antisense injection, while there were no changes in protein levels at 2, 12 and 24 h.

Negative_regulation (decrease) of Gialpha2

1) Confidence 0.34 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9729412 Disease Relevance 0 Pain Relevance 0.96

General Comments

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