INT77371

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Context Info
Confidence 0.45
First Reported 1998
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 0.45
Pain Relevance 2.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cebpz)
Anatomy Link Frequency
blood 6
vasculature 2
Cebpz (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sumatriptan 12 100.00 Very High Very High Very High
ergotamine 12 100.00 Very High Very High Very High
Migraine 6 100.00 Very High Very High Very High
halothane 3 99.36 Very High Very High Very High
5HT 3 90.00 High High
dopamine receptor 3 88.00 High High
agonist 3 80.68 Quite High
imagery 62 76.00 Quite High
isoflurane 12 55.20 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 6 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ergotamine shifted the lower blood pressure limit of CBF autoregulation towards higher blood pressures from 60 +/- 3 mmHg to 82 +/- 4 mmHg (p<0.01), but did not significantly affect the upper blood pressure limit of CBF autoregulation.
Neg (not) Regulation (affect) of Regulation (autoregulation) of CBF in blood associated with ergotamine
1) Confidence 0.45 Published 1998 Journal Cephalalgia Section Abstract Doc Link 9731933 Disease Relevance 0.14 Pain Relevance 0.80
This oxygen gradient along the arterial vasculature allows the mechanisms regulating CBF to also regulate the delivery of oxygen to sub-serving areas.
Regulation (regulate) of Regulation (regulating) of CBF in vasculature
2) Confidence 0.36 Published 2010 Journal Frontiers in Neuroenergetics Section Body Doc Link PMC2899518 Disease Relevance 0 Pain Relevance 0.06
The results obtained showed that the calculated CMRO2 dynamics lagged changes in CBF by 2.2?
Regulation (lagged) of Regulation (changes) of CBF
3) Confidence 0.26 Published 2010 Journal Frontiers in Neuroenergetics Section Body Doc Link PMC2899518 Disease Relevance 0 Pain Relevance 0.07
Sumatriptan had no significant effects on the blood pressure limits of CBF autoregulation.
Neg (no) Regulation (effects) of Regulation (autoregulation) of CBF in blood associated with sumatriptan
4) Confidence 0.24 Published 1998 Journal Cephalalgia Section Abstract Doc Link 9731933 Disease Relevance 0.14 Pain Relevance 0.76
The effect of the migraine drugs ergotamine and sumatriptan on the cerebral blood flow (CBF) autoregulation was studied in halothane/nitrous oxide-anesthetized normotensive Wistar Kyoto rats.
Regulation (effect) of Regulation (autoregulation) of CBF in blood associated with sumatriptan, migraine, halothane and ergotamine
5) Confidence 0.24 Published 1998 Journal Cephalalgia Section Abstract Doc Link 9731933 Disease Relevance 0.17 Pain Relevance 0.74

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