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Context Info
Confidence 0.43
First Reported 1998
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 55
Total Number 56
Disease Relevance 39.32
Pain Relevance 5.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
respiratory 6
blood 1
PCs 1
B cells 1
PCs 1
PCS (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 70 99.58 Very High Very High Very High
antagonist 9 99.08 Very High Very High Very High
Pain 219 98.60 Very High Very High Very High
central pain 2 97.68 Very High Very High Very High
Pain score 4 94.20 High High
qutenza 2 93.20 High High
Duloxetine 230 92.76 High High
rheumatoid arthritis 107 92.20 High High
Mcgill questionnaire 5 90.56 High High
Myofascial pain syndrome 4 89.60 High High
Disease Link Frequency Relevance Heat
Weight Loss 28 100.00 Very High Very High Very High
Food Hypersensitivity 8 100.00 Very High Very High Very High
Weight Gain 29 99.96 Very High Very High Very High
Fibromyalgia 69 99.58 Very High Very High Very High
Cough 59 99.48 Very High Very High Very High
Rheumatic Diseases 24 99.48 Very High Very High Very High
Respiratory Disease 107 99.44 Very High Very High Very High
Anaerobic Bacterial Infections 7 99.44 Very High Very High Very High
Pulmonary Disease 299 99.28 Very High Very High Very High
Asthma 355 99.18 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The impairment with the highest direct impact was severe Musculoskeletal problem reducing PCS by 8 points (Table 3).
Negative_regulation (reducing) of PCS
1) Confidence 0.43 Published 2007 Journal Health Qual Life Outcomes Section Body Doc Link PMC2042974 Disease Relevance 0.31 Pain Relevance 0.12
THE AIM OF THE STUDY: To estimate the prevalence of PCS in patients after cholecystectomy performed in Department of General and Colorectal Surgery of Medical University in Lodz.
Negative_regulation (prevalence) of PCS
2) Confidence 0.37 Published 2008 Journal Pol. Merkur. Lekarski Section Body Doc Link 19112835 Disease Relevance 0.10 Pain Relevance 0
PCS was significantly impaired in nonsmokers (P = 0.028), in those who underwent less invasive surgery (P = 0.007), in those who had pain at onset of the disease (P = 0.002), and in those who received multimodality treatment (P = 0.013).
Negative_regulation (impaired) of PCS
3) Confidence 0.34 Published 2010 Journal Eur J Gastroenterol Hepatol Section Body Doc Link 19491696 Disease Relevance 0.06 Pain Relevance 0
In males, the results confirmed that only social support predicted the PCS and MCS scores, while other variables did not predict either score.
Negative_regulation (predicted) of PCS
4) Confidence 0.34 Published 2008 Journal Biopsychosoc Med Section Body Doc Link PMC2569038 Disease Relevance 0 Pain Relevance 0
A population representative sample of 4086 adults of the cross-sectional epidemiologic 'Study of Health in Pomerania' (SHIP-0) (age range 20-80 years, female 50.2%) was divided in two groups by the presence or absence of a PCS.
Negative_regulation (absence) of PCS
5) Confidence 0.33 Published 2008 Journal J Oral Rehabil Section Abstract Doc Link 18699970 Disease Relevance 0.56 Pain Relevance 0.60
However, patients with respiratory disease reported worse PCS than patients with other chronic disease, and the combination of cardiovascular and respiratory diseases had a negative synergistic effect on the PCS [10].
Negative_regulation (effect) of PCS in respiratory associated with respiratory disease and chronic disease
6) Confidence 0.32 Published 2007 Journal Health Qual Life Outcomes Section Body Doc Link PMC2042974 Disease Relevance 0.72 Pain Relevance 0.09
Our data confirm the same synergistic effect of these systems on PCS since, in our multivariate model, cardiac problems are not significant, respiratory problems only approach significance and their interaction is highly significant i.e. their combined effect decreases more the PCS than the sum of the independent negative effect of each condition.
Negative_regulation (decreases) of PCS in respiratory
7) Confidence 0.32 Published 2007 Journal Health Qual Life Outcomes Section Body Doc Link PMC2042974 Disease Relevance 0.71 Pain Relevance 0.09
Our data confirm the same synergistic effect of these systems on PCS since, in our multivariate model, cardiac problems are not significant, respiratory problems only approach significance and their interaction is highly significant i.e. their combined effect decreases more the PCS than the sum of the independent negative effect of each condition.
Negative_regulation (decreases) of PCS in respiratory
8) Confidence 0.32 Published 2007 Journal Health Qual Life Outcomes Section Body Doc Link PMC2042974 Disease Relevance 0.55 Pain Relevance 0.05
Six months later subjects completed the SF-36 PCS and the number of healthcare contacts during follow-up was recorded.
Negative_regulation (completed) of SF-36 PCS
9) Confidence 0.32 Published 2008 Journal Pain Section Abstract Doc Link 17611036 Disease Relevance 1.47 Pain Relevance 0.88
In patients suspected of a connective tissue disease, no relationship was found between the presence of serum ANAs and the number of CD27++ PCs.
Negative_regulation (number) of PCs in PCs associated with disease
10) Confidence 0.27 Published 2007 Journal J Clin Immunol Section Abstract Doc Link PMC2039801 Disease Relevance 0.94 Pain Relevance 0
We found that patients with bacterial infections reached similar frequencies and absolute numbers of CD27++ PCs as previously reported in active SLE patients (12, 14).
Negative_regulation (numbers) of PCs associated with systemic lupus erythematosus and bacterial infection
11) Confidence 0.27 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.20 Pain Relevance 0.03
In support, others described that patients with inactive SLE had increased frequencies of CD27++ PCs but normal absolute numbers of PCs, whereas patients with active SLE had elevated frequencies and absolute numbers of PCs (12, 14).
Negative_regulation (numbers) of PCs associated with systemic lupus erythematosus
12) Confidence 0.27 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.98 Pain Relevance 0.06
A weak relationship between the number of CD27++ PCs and the occurrence of anti-ENA antibodies was also observed in a prior study (25).
Negative_regulation (number) of PCs
13) Confidence 0.27 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.90 Pain Relevance 0
Large numbers of PCs were detectable in blood on day 6 and 7 after immunization and disappeared from the blood after day 8 (29).
Negative_regulation (numbers) of PCs in blood associated with immunization
14) Confidence 0.27 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.68 Pain Relevance 0.03
The absolute number of PCs at day 0 was moderately higher than controls (P = 0.03) (Fig. 1).
Negative_regulation (number) of PCs
15) Confidence 0.27 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.37 Pain Relevance 0
Thus, the presence of serum ANAs itself does not coincide with increased numbers of IgD+ CD38++ transitional B cells and CD27++ PCs as characteristically seen in SLE patients.
Negative_regulation (numbers) of PCs in B cells associated with systemic lupus erythematosus
16) Confidence 0.27 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.09 Pain Relevance 0
Hussain et al. [11] reported PCS and MCS summary scores and results according to several patient characteristics.
Negative_regulation (reported) of PCS
17) Confidence 0.27 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1187913 Disease Relevance 0.33 Pain Relevance 0.09
In an analysis of the factors associated with the HRQL at 6 and 12 months after discharge, Beck et al. [7] observed that age was a factor that predicted an impaired PCS in both cases, with the older patients obtaining lower scores.
Negative_regulation (impaired) of PCS
18) Confidence 0.25 Published 2006 Journal BMC Public Health Section Body Doc Link PMC1413520 Disease Relevance 0.45 Pain Relevance 0.07
However Beck et al [7] find a decrease in the scores of the PCS in the patients who have had revascularisation.
Negative_regulation (decrease) of PCS
19) Confidence 0.25 Published 2006 Journal BMC Public Health Section Body Doc Link PMC1413520 Disease Relevance 0.23 Pain Relevance 0
The variables revascularisation, age, and the interaction between previous history of coronary heart disease (CHD) and the presence of one or more risk factors explained 16.6% of the decrease in the PCS.
Negative_regulation (decrease) of PCS in heart associated with coronary artery disease
20) Confidence 0.25 Published 2006 Journal BMC Public Health Section Abstract Doc Link PMC1413520 Disease Relevance 0.25 Pain Relevance 0

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