INT78255

Context Info Confidence 0.12 First Reported 1998 Last Reported 1998 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.59 Pain Relevance 0.62

signal transduction (Npy2r) plasma membrane (Npy2r) signal transducer activity (Npy2r)

Anatomy Link Frequency neuron 1 Npy2r (Mus musculus)

Pain Link Frequency Relevance Heat Analgesic 2 97.92 Pain 2 95.80 tail-flick 2 89.24 Sciatic nerve 2 78.04 Neuropeptide 4 75.00 dorsal root ganglion 2 75.00 Root ganglion neuron 2 75.00

Disease Link Frequency Relevance Heat Pain 2 95.80 Sprains And Strains 2 88.32 Nociception 2 85.48 Ganglion Cysts 2 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Although significant differences in levels of Y1- and especially Y2-R mRNAs were observed between wild type and NPY-deficient mice, they were only moderate.

Transcription (levels) of Y2-R

1) Confidence 0.12 Published 1998 Journal Regul. Pept. Section Abstract Doc Link 9802405 Disease Relevance 0.32 Pain Relevance 0.34

Y1- and Y2-R mRNAs were found mainly in small DRG neuron profiles.

Transcription (found) of Y2-R in neuron

2) Confidence 0.12 Published 1998 Journal Regul. Pept. Section Abstract Doc Link 9802405 Disease Relevance 0.28 Pain Relevance 0.28

General Comments

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