INT78854

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Context Info
Confidence 0.14
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (APP, IL6) aging (IL6) Golgi apparatus (APP)
extracellular matrix organization (APP) DNA binding (APP) cytoplasm (APP)
Anatomy Link Frequency
T98G 2
APP (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 1 94.00 High High
Inflammation 3 79.12 Quite High
Paracetamol 2 75.00 Quite High
Analgesic 1 68.00 Quite High
Central nervous system 1 59.92 Quite High
cINOD 1 37.92 Quite Low
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 3 100.00 Very High Very High Very High
Anaplastic Astrocytoma 2 100.00 Very High Very High Very High
Disease 1 96.72 Very High Very High Very High
INFLAMMATION 5 93.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study shows that beta-amyloid can stimulate human astrocytoma cells (T98G) to secrete the proinflammatory factors interleukin-6 and prostaglandins.
beta-amyloid Positive_regulation (stimulate) of Localization (secrete) of interleukin-6 in T98G associated with anaplastic astrocytoma and alzheimer's dementia
1) Confidence 0.14 Published 1998 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9845273 Disease Relevance 0.79 Pain Relevance 0.37

General Comments

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