INT78862

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Context Info
Confidence 0.36
First Reported 1998
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.76
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Adam17) cell motility (Adam17) cell adhesion (Adam17)
plasma membrane (Adam17) cytoplasm (Adam17)
Adam17 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 2 99.44 Very High Very High Very High
palliative 2 97.44 Very High Very High Very High
aspirin 6 92.28 High High
cINOD 2 89.40 High High
tolerance 7 26.64 Quite Low
imagery 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 56 98.42 Very High Very High Very High
Disease 5 97.92 Very High Very High Very High
Injury 4 90.64 High High
Recurrence 3 89.08 High High
Necrosis 3 87.20 High High
Cancer 56 86.84 High High
Liver Disease 9 70.32 Quite High
Hepatitis B Virus Infection 1 67.92 Quite High
Hepatitis 1 67.40 Quite High
Thrombosis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TACE inhibitors prevent TNFalpha release and protect against TNFalpha-mediated disease.
Negative_regulation (inhibitors) of TACE associated with disease
1) Confidence 0.36 Published 1998 Journal Aliment. Pharmacol. Ther. Section Abstract Doc Link 9845404 Disease Relevance 0.44 Pain Relevance 0.22
Radiofrequency ablation therapy and percutaneous ethanol injection therapy are also used as curative treatments for HCC.5 Because HCC is frequently diagnosed at the intermediate or advanced stages, transarterial chemoembolization (TACE), the most popular nonsurgical alternative, is often used as a palliative treatment,6,7 however, effective only in limited occasion.
Negative_regulation (chemoembolization) of TACE associated with hepatocellular cancer and palliative
2) Confidence 0.35 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2768232 Disease Relevance 1.32 Pain Relevance 0.10
Agents that prevent TNFalpha mRNA transcription, e.g. lisophylline, PGE2, interleukin-10 and 8-BrcAMP, or TACE inhibitors, e.g.
Negative_regulation (inhibitors) of TACE
3) Confidence 0.23 Published 1998 Journal Aliment. Pharmacol. Ther. Section Body Doc Link 9845404 Disease Relevance 0 Pain Relevance 0

General Comments

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