INT79432

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Context Info
Confidence 0.23
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 6.59
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Calb2) cellular_component (Calb2) biological_process (Calb2)
cytoplasm (Calb2)
Anatomy Link Frequency
smooth muscle 1
muscle 1
Calb2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 1 84.08 Quite High
Neuropeptide 3 82.64 Quite High
Pain 15 79.80 Quite High
imagery 9 73.08 Quite High
substance P 1 63.28 Quite High
abdominal pain 2 59.88 Quite High
Somatostatin 1 32.64 Quite Low
Dismenorea 1 21.96 Low Low
Inflammation 1 19.16 Low Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 84 99.90 Very High Very High Very High
Malignant Neoplastic Disease 10 98.78 Very High Very High Very High
Multiple System Atrophy 4 96.00 Very High Very High Very High
Adenocarcinoma 11 95.68 Very High Very High Very High
Cystadenocarcinoma 38 92.96 High High
Fibroma 33 91.52 High High
Ovarian Cancer 28 90.00 High High
Granulosa Cell Tumor 4 89.92 High High
Rhinitis 5 87.20 High High
Synovial Sarcoma 60 84.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The tumor was negative for mucin, carcinoembryonic antigen, alpha-fetoprotein, calretinin, CD31, and chromogranin.
Positive_regulation (negative) of calretinin associated with cancer
1) Confidence 0.23 Published 2004 Journal Arch. Pathol. Lab. Med. Section Abstract Doc Link 14736268 Disease Relevance 0.76 Pain Relevance 0.11
The tumor cells were immunoreactive for estrogen receptor, inhibin, vimentin, and calretinin.
Positive_regulation (immunoreactive) of calretinin associated with cancer
2) Confidence 0.12 Published 2002 Journal Diagn. Cytopathol. Section Abstract Doc Link 12112830 Disease Relevance 0.51 Pain Relevance 0.08
All were immunoreactive for the synthesizing enzyme for acetylcholine, choline acetyltransferase, and some were also immunoreactive for calretinin.
Positive_regulation (immunoreactive) of calretinin
3) Confidence 0.04 Published 1998 Journal Neuroscience Section Abstract Doc Link 9881879 Disease Relevance 0 Pain Relevance 0.16
Immunohistochemical staining of the malignant ascitic cells was positive for CA 125, WT-1, CK7 and ER but negative for CK20, TTF-1, PR, Calretinin and BRST-2.
Positive_regulation (negative) of Calretinin associated with malignant neoplastic disease
4) Confidence 0.03 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC2204026 Disease Relevance 1.08 Pain Relevance 0.15
Immunohistochemically, the tumor cells were positive for the epithelial membrane antigen(EMA), calretinin, cytokeratin(CK), vimentin (VIM), but negative for smooth muscle actin(SMA), muscle specific actin(MSA), CD117 and S100.
Positive_regulation (positive) of calretinin in muscle associated with cancer and multiple system atrophy
5) Confidence 0.03 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2995789 Disease Relevance 0.89 Pain Relevance 0
The spindle cells were positive for epithelial membrane antigen (EMA), calretinin, cytokeratin (CK), vimentin (VIM) and proliferating cell nuclear antigen (PCNA), but negative for smooth muscle actin(SMA), muscle specific actin(MSA), CD117 and S100.
Positive_regulation (positive) of calretinin in smooth muscle associated with multiple system atrophy
6) Confidence 0.03 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2995789 Disease Relevance 1.08 Pain Relevance 0.06
Immunihistochemically, the minor sex cord elements are positive for inhibin, calretinin, CD99, CD56, antikeratin antibody KL1 and MIC. [2,6]
Positive_regulation (positive) of calretinin
7) Confidence 0.02 Published 2008 Journal Cases J Section Body Doc Link PMC2579288 Disease Relevance 1.14 Pain Relevance 0
Immunihistochemically, the minor sex cord elements are positive for inhibin, calretinin, CD99, CD56, antikeratin antibody KL1 and MIC [2,7].
Positive_regulation (positive) of calretinin
8) Confidence 0.02 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC2217290 Disease Relevance 1.13 Pain Relevance 0.06

General Comments

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