INT80194

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Context Info
Confidence 0.04
First Reported 1999
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.85
Pain Relevance 2.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Rab38) vesicle-mediated transport (Rab38) Golgi apparatus (Rab38)
endoplasmic reticulum (Rab38) GTPase activity (Rab38) cytoplasm (Rab38)
Anatomy Link Frequency
Sensory neuron 1
nerve 1
DRG 1
pyramidal layer 1
Rab38 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 9 100.00 Very High Very High Very High
Nerve growth factor 20 98.94 Very High Very High Very High
dorsal root ganglion 14 98.40 Very High Very High Very High
tetrodotoxin 2 94.44 High High
Pain threshold 2 93.32 High High
Pain 2 93.20 High High
hypoalgesia 2 79.44 Quite High
allodynia 1 78.00 Quite High
Thermal hyperalgesia 1 76.88 Quite High
lumbar region 1 74.72 Quite High
Disease Link Frequency Relevance Heat
Nociception 2 99.92 Very High Very High Very High
Ganglion Cysts 14 98.40 Very High Very High Very High
Syndrome 2 93.60 High High
Pain 4 93.32 High High
Hypoalagesia 2 79.44 Quite High
Neuropathic Pain 3 58.48 Quite High
Injury 1 51.60 Quite High
Cognitive Disorder 7 5.00 Very Low Very Low Very Low
Sleep Disorders 4 5.00 Very Low Very Low Very Low
Amnesia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to examine the effects of temperature on SPWs and ripple oscillation, the temperature in the recording chamber was changed systematically while continuously recording SPW-R activity from the CA1 pyramidal layer.
Transcription (activity) of SPW-R in pyramidal layer
1) Confidence 0.04 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1950312 Disease Relevance 0 Pain Relevance 0
The data suggest that NGF has a major role in the maintenance of steady-state levels of TTX-R sodium currents and SNS mRNA in IB4(-) DRG neurons in adult rats in vivo.
Transcription (levels) of TTX-R in DRG associated with dorsal root ganglion and nerve growth factor
2) Confidence 0.01 Published 1999 Journal J. Neurophysiol. Section Abstract Doc Link 10036280 Disease Relevance 0.58 Pain Relevance 0.76
TTX-R sodium currents and SNS mRNA expression have been shown to be modulated by nerve growth factor (NGF) in vitro and in vivo.
Transcription (expression) of TTX-R in nerve associated with nerve growth factor
3) Confidence 0.01 Published 1999 Journal J. Neurophysiol. Section Abstract Doc Link 10036280 Disease Relevance 0.73 Pain Relevance 0.82
Sensory neuron specific TTX-R sodium channel NaV1. 8 transcript was down-regulated after antisense oligonucleotide injection at the dosage of 45 microg as compared with that in CCI group (P < 0.01), and it was even greater at the dosage of 90 microg.
Transcription (transcript) of TTX-R in Sensory neuron associated with sodium channel
4) Confidence 0.01 Published 2005 Journal J. Huazhong Univ. Sci. Technol. Med. Sci. Section Abstract Doc Link 16696329 Disease Relevance 0.55 Pain Relevance 0.77

General Comments

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