INT81657

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Context Info
Confidence 0.15
First Reported 1999
Last Reported 2006
Negated 0
Speculated 0
Reported most in Title
Documents 5
Total Number 5
Disease Relevance 1.90
Pain Relevance 2.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CPOX, PTGS1) cytoplasm (CPOX, PTGS1) oxidoreductase activity (CPOX, PTGS1)
nuclear envelope (PTGS1) mitochondrion (CPOX) aging (PTGS1)
CPOX (Homo sapiens)
PTGS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 15 100.00 Very High Very High Very High
COX-2 inhibitor 4 100.00 Very High Very High Very High
COX2 4 99.98 Very High Very High Very High
Pain 4 99.98 Very High Very High Very High
cOX1 2 99.98 Very High Very High Very High
cva 2 99.98 Very High Very High Very High
Hyperalgesia 4 99.28 Very High Very High Very High
Inflammation 6 97.12 Very High Very High Very High
cINOD 7 96.36 Very High Very High Very High
Analgesic 2 92.32 High High
Disease Link Frequency Relevance Heat
Hyperalgesia 4 99.28 Very High Very High Very High
Stomach Cancer 24 98.64 Very High Very High Very High
Cancer 71 97.16 Very High Very High Very High
INFLAMMATION 7 97.12 Very High Very High Very High
Stress 2 96.20 Very High Very High Very High
Fever 4 94.72 High High
Neurological Disease 4 80.64 Quite High
Disease 4 66.72 Quite High
Pain 2 57.16 Quite High
Colon Cancer 2 56.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two isoforms of cyclooxygenase (COX), the enzyme that catalyzes the conversion of arachidonic acid to prostanoids, are now recognized: a constitutively expressed COX-1 and a highly regulated COX-2.
COX Binding (recognized) of cyclooxygenase
1) Confidence 0.15 Published 1999 Journal Crit Rev Neurobiol Section Abstract Doc Link 10223523 Disease Relevance 0.37 Pain Relevance 0.10
Two isoforms of cyclooxygenase (COX), the enzyme that catalyzes the conversion of arachidonic acid to prostanoids, are now recognized: a constitutively expressed COX-1 and a highly regulated COX-2.
COX Binding (recognized) of cyclooxygenase
2) Confidence 0.15 Published 1999 Journal Crit Rev Neurobiol Section Abstract Doc Link 10223523 Disease Relevance 0.37 Pain Relevance 0.10
[Cyclooxygenase (COX)-2 selective inhibitors: aspirin, a dual COX-1/COX-2 inhibitor, to COX-2 selective inhibitors].
COX Binding (aspirin) of Cyclooxygenase associated with aspirin and cox-2 inhibitor
3) Confidence 0.09 Published 2001 Journal Nippon Yakurigaku Zasshi Section Title Doc Link 11577463 Disease Relevance 0.49 Pain Relevance 1.09
[Cyclooxygenase (COX)-2 selective inhibitors: aspirin, a dual COX-1/COX-2 inhibitor, to COX-2 selective inhibitors].
COX Binding (aspirin) of Cyclooxygenase associated with aspirin and cox-2 inhibitor
4) Confidence 0.09 Published 2001 Journal Nippon Yakurigaku Zasshi Section Title Doc Link 11577463 Disease Relevance 0.48 Pain Relevance 1.08
Cyclooxygenase (COX) is a bifunctional enzyme with cyclooxygenase and peroxidase activities.
COX Binding (enzyme) of cyclooxygenase
5) Confidence 0.00 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721998 Disease Relevance 0.20 Pain Relevance 0

General Comments

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