INT81769

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Context Info
Confidence 0.35
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Neurod1) transport (Chrna4) DNA binding (Neurod1)
cytoplasm (Neurod1) signal transduction (Chrna4) nucleocytoplasmic transport (Neurod1)
Chrna4 (Mus musculus)
Neurod1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nicotine 6 99.76 Very High Very High Very High
Raphe magnus 1 97.72 Very High Very High Very High
antinociception 2 97.64 Very High Very High Very High
tail-flick 1 95.24 Very High Very High Very High
Antinociceptive 2 91.32 High High
Pain 2 71.76 Quite High
Disease Link Frequency Relevance Heat
Pain 1 71.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The alpha4 nAChR subunit, possibly associated with the beta2 nAChR subunit, is therefore crucial for nicotine-elicited antinociception.
alpha4 nAChR subunit Binding (associated) of beta2 associated with antinociception and nicotine
1) Confidence 0.35 Published 1999 Journal Nature Section Abstract Doc Link 10235262 Disease Relevance 0.07 Pain Relevance 0.69

General Comments

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