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Context Info
Confidence 0.44
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.04
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1b) aging (Il1b) extracellular region (Il1b)
Anatomy Link Frequency
THP-1 2
Il1b (Mus musculus)
Pain Link Frequency Relevance Heat
Analgesic 6 94.24 High High
Inflammation 8 92.72 High High
carrageenan induced 1 66.12 Quite High
cINOD 1 50.00 Quite Low
Pain 2 25.00 Low Low
COX2 1 10.00 Low Low
cOX1 1 10.00 Low Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 5 97.32 Very High Very High Very High
INFLAMMATION 8 92.72 High High
Necrosis 1 75.72 Quite High
Cancer 1 75.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In stimulated monocytic cells (THP-1), lornoxicam showed a marked inhibition of IL-6 formation (IC50 54 microM) while the formation ofTNF-alpha, IL-1beta and IL-8 was only moderately affected.
Regulation (affected) of Positive_regulation (formation) of IL-1beta in THP-1
1) Confidence 0.44 Published 1999 Journal Inflamm. Res. Section Body Doc Link 10450786 Disease Relevance 0 Pain Relevance 0
MKGS also affected the levels of IL-1beta, TNF-alpha and NO induced by lambda-carrageenan.
Regulation (affected) of Positive_regulation (induced) of IL-1beta in MKGS
2) Confidence 0.44 Published 2010 Journal Am. J. Chin. Med. Section Abstract Doc Link 20503470 Disease Relevance 1.04 Pain Relevance 0.58

General Comments

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