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Context Info
Confidence 0.02
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Il1b, SERPINA3) extracellular space (Il1b) aging (Il1b)
nucleus (SERPINA3) intracellular (SERPINA3) DNA binding (SERPINA3)
Anatomy Link Frequency
microglial cells 1
Il1b (Rattus norvegicus)
SERPINA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 83.20 Quite High
Inflammation 3 75.00 Quite High
Analgesic 1 72.84 Quite High
cINOD 2 71.04 Quite High
Disease Link Frequency Relevance Heat
Anaplastic Astrocytoma 1 97.52 Very High Very High Very High
Disease 4 90.56 High High
INFLAMMATION 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that tepoxalin markedly inhibits IL-1beta-induced IL-6 and ACT synthesis in astrocytes and the synthesis of IL-1beta and IL-6 in lipopolysaccharide (LPS)-stimulated microglial cells.
IL-1beta Positive_regulation (induced) of ACT in microglial cells
1) Confidence 0.02 Published 1999 Journal Neuropharmacology Section Abstract Doc Link 10471086 Disease Relevance 0.50 Pain Relevance 0.41

General Comments

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