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Context Info
Confidence 0.17
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Aqp2) protein complex (Aqp2) transmembrane transport (Aqp2)
cytoplasm (Aqp2) response to stress (Avp) signal transducer activity (Avp)
Anatomy Link Frequency
duct 1
Avp (Rattus norvegicus)
Aqp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 3 97.32 Very High Very High Very High
Clonidine 6 96.64 Very High Very High Very High
anesthesia 1 25.00 Low Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aquaporin-2 (AQP-2), the major water channel responsible for water balance, has been shown to be regulated by the binding of vasopressin to V(2) vasopressin receptors in the medullary collecting duct. alpha(2)-Adrenoceptor agonists such as clonidine have been associated with an increase in free water clearance that was secondary to an inhibition of the ability of vasopressin to increase cAMP levels in the collecting ducts.
vasopressin Binding (binding) of AQP-2 in duct associated with agonist and clonidine
1) Confidence 0.17 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10525117 Disease Relevance 0 Pain Relevance 0.35

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