INT8480

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Context Info
Confidence 0.78
First Reported 1992
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.73
Pain Relevance 1.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PIAS1) nucleus (PIAS1) enzyme binding (PIAS1)
DNA binding (PIAS1) ligase activity (PIAS1)
Anatomy Link Frequency
lumen 1
T cells 1
PIAS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Gabapentin 18 100.00 Very High Very High Very High
gABA 3 92.00 High High
anticonvulsant 1 67.32 Quite High
Analgesic 3 25.00 Low Low
Opioid 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
drug abuse 3 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 64 99.46 Very High Very High Very High
Hepatitis C Virus Infection 117 99.26 Very High Very High Very High
Opiate Addiction 79 99.08 Very High Very High Very High
Partial Seizures 2 79.32 Quite High
Drug Dependence 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Liver Disease 2 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 5.00 Very Low Very Low Very Low
Viral Infection 2 5.00 Very Low Very Low Very Low
Hepatitis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The derivative product of GBP was extracted from the 8.5 mL of acidic solution (source phase) into an organic phase (dihexyl ether) impregnated in the pores of a hollow fiber and finally back-extracted into 24 microL of the basic solution (pH 9.1) located inside the lumen of the hollow fiber (receiving phase).
Gene_expression (product) of GBP in lumen associated with gabapentin
1) Confidence 0.78 Published 2010 Journal Anal. Chim. Acta Section Abstract Doc Link 20417334 Disease Relevance 0 Pain Relevance 0.46
After 24 h, GBP could only be recovered in the CSF of the patient given 1200 mg.
Gene_expression (recovered) of GBP associated with gabapentin
2) Confidence 0.58 Published 1992 Journal Epilepsy Res. Section Abstract Doc Link 1373372 Disease Relevance 0.15 Pain Relevance 1.12
We found that although heroin use or heroin use plus HCV infection had little effects on the expression of PIAS-1, PIAS-x and PIAS-y in CD56+ T cells, the levels of PIAS-3 gene expression in CD56+ T cells from the HCV-infected heroin users was significantly increased, comparing with the control subjects (Fig. 7).
Gene_expression (expression) of PIAS-1 in T cells associated with hepatitis c virus infection, opiate addiction and infection
3) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2834757 Disease Relevance 1.58 Pain Relevance 0

General Comments

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