INT84998

Context Info Confidence 0.69 First Reported 1999 Last Reported 1999 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0.45

transport (SLC10A1) small molecule metabolic process (SLC10A1) plasma membrane (SLC10A1)

SLC10A1 (Homo sapiens)

Pain Link Frequency Relevance Heat lidocaine 1 99.38 antiarrhythmic agent 1 98.70 Bile 9 89.48

Disease Link Frequency Relevance Heat Disease 1 83.60 Pox Virus Infection 1 78.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A number of drugs, including peptidomimetic renin inhibitors, propranolol, cyclosporin, and progesterone, were found to be potent inhibitors, whereas antiarrhythmic agents, including bupivicaine, lidocaine, and quinidine, were found to enhance NTCP activity.

Positive_regulation (enhance) of NTCP associated with antiarrhythmic agent and lidocaine

1) Confidence 0.69 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10565843 Disease Relevance 0.16 Pain Relevance 0.45

General Comments

This test has worked.