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Context Info
Confidence 0.00
First Reported 1999
Last Reported 1999
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Cct2) protein folding (Cct2) signal transduction (Chrna3)
transport (Chrna3) plasma membrane (Chrna3) nucleus (Cct2)
Cct2 (Mus musculus)
Chrna3 (Mus musculus)
Pain Link Frequency Relevance Heat
monoamine 2 99.52 Very High Very High Very High
agonist 2 95.68 Very High Very High Very High
Central nervous system 1 75.00 Quite High
tetrodotoxin 1 72.20 Quite High
Serotonin 1 71.12 Quite High
Dopamine 1 70.48 Quite High
Nicotine 2 66.80 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 1 90.72 High High
Increased Venous Pressure Under Development 1 58.32 Quite High
Nicotine Addiction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Considering neurochemical, pharmacological and electrophysiological evidence it seems likely that presynaptic nAChRs on monoaminergic fibers are composed of alpha3 or alpha4 subunits in combination with the beta2 subunit.
beta2 subunit Spec (likely) Binding (combination) of alpha3 associated with monoamine
1) Confidence 0.00 Published 1999 Journal Brain Res. Brain Res. Rev. Section Abstract Doc Link 10567725 Disease Relevance 0.15 Pain Relevance 0.38

General Comments

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