INT8511

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Context Info
Confidence 0.80
First Reported 1992
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 3.27
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Esr1) nucleus (Esr1) enzyme binding (Esr1)
DNA binding (Esr1) protein complex (Esr1) transcription factor binding (Esr1)
Anatomy Link Frequency
neurons 1
iris 1
Esr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Snapping jaw 12 89.92 High High
Inflammation 10 84.40 Quite High
Enkephalin 2 83.64 Quite High
antagonist 1 78.96 Quite High
spinal inflammation 1 68.44 Quite High
spondylitis 1 65.12 Quite High
rheumatoid arthritis 2 57.16 Quite High
Arthritis 17 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Uveitis 9 99.92 Very High Very High Very High
Osteomyelitis 148 98.54 Very High Very High Very High
INFLAMMATION 10 84.40 Quite High
Overdose 1 82.48 Quite High
Temporomandibular Joint Syndrome 12 78.88 Quite High
Congenital Anomalies 2 72.16 Quite High
Discitis 5 70.44 Quite High
Low Back Pain 3 68.44 Quite High
Disease 13 67.36 Quite High
Bacteremia 1 57.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to the nuclear localization of ER alpha, a weak immunoreaction appeared in the cytoplasm of some ER alpha-positive cells.
Localization (localization) of ER alpha
1) Confidence 0.80 Published 2003 Journal The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology Section Abstract Doc Link 12973717 Disease Relevance 0.51 Pain Relevance 0.47
In addition to the nuclear localization of ER alpha, a weak immunoreaction appeared in the cytoplasm of some ER alpha-positive cells.
Localization (localization) of ER alpha
2) Confidence 0.70 Published 2003 Journal The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology Section Abstract Doc Link 12973717 Disease Relevance 0.51 Pain Relevance 0.47
Double label ultrastructural localization of estrogen receptor (ER)-ir neurons and ENK-ir fibers was performed using the chromogens 3,3',5,5'-tetramethylbenzidine (TMB) and diaminobenzidine tetrahydrochloride (DAB), respectively.
Localization (localization) of estrogen receptor in neurons
3) Confidence 0.51 Published 1992 Journal Brain Res. Section Abstract Doc Link 1374283 Disease Relevance 0 Pain Relevance 0.08
Estrogen receptor immunoreactivity was found in the nucleus of vascular endothelium and in some stromal cells of the iris-ciliary body.
Localization (found) of Estrogen receptor in iris
4) Confidence 0.51 Published 1999 Journal J. Immunol. Section Abstract Doc Link 10384138 Disease Relevance 0.96 Pain Relevance 0.18
In other studies, ESR was elevated in 88% to 92% of osteomyelitis patients on admission, and the rate of positive test and median or mean ESR value depended on whether there patients had the acute, subacute or chronic form.[4,37] The fact that an ESR ?
Localization (value) of ESR associated with osteomyelitis
5) Confidence 0.45 Published 2008 Journal BMC Pediatr Section Body Doc Link PMC2588573 Disease Relevance 1.21 Pain Relevance 0.06
Some UV filters exhibit estrogenic or antiandrogenic activity (Holbech et al. 2002; Inui et al. 2003; Ma et al. 2003; Mueller et al. 2003; Schlumpf et al. 2001a; Schreurs et al. 2002; Tinwell et al. 2002). 4-MBC, a UV filter in sunscreens, and 3-benzylidene camphor, a structurally related UV absorber, are interesting because they exhibit preference for estrogen receptor (ER)-?
Localization (preference) of estrogen receptor
6) Confidence 0.27 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC2174398 Disease Relevance 0.07 Pain Relevance 0

General Comments

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