INT85337

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Context Info
Confidence 0.34
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.32
Pain Relevance 1.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Slc9a3r2) nucleus (Slc9a3r2) cytoplasm (Slc9a3r2)
Anatomy Link Frequency
red blood cells 1
knee 1
Slc9a3r2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 25 98.68 Very High Very High Very High
rheumatoid arthritis 12 95.68 Very High Very High Very High
tetrodotoxin 1 95.60 Very High Very High Very High
cva 5 5.00 Very Low Very Low Very Low
Osteoarthritis 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 19 98.68 Very High Very High Very High
Rheumatoid Arthritis 12 95.68 Very High Very High Very High
Hyperkalemia 1 89.36 High High
Disease 2 74.32 Quite High
Postoperative Hemorrhage 1 63.16 Quite High
Obesity 33 50.00 Quite Low
Anaemia 1 42.60 Quite Low
Pressure Volume 2 Under Development 7 32.80 Quite Low
Injury 7 5.00 Very Low Very Low Very Low
Infection 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Oxford knee scores decreased significantly one year after surgery in both the TKA group and the UKA group.
Negative_regulation (decreased) of TKA in knee
1) Confidence 0.34 Published 2008 Journal Knee Surg Sports Traumatol Arthrosc Section Abstract Doc Link 18696051 Disease Relevance 0.09 Pain Relevance 0.09
Long-term myocardial preservation: beneficial and additive effects of polarized arrest (Na+-channel blockade), Na+/H+-exchange inhibition, and Na+/K+/2Cl- -cotransport inhibition combined with calcium desensitization.
Negative_regulation (inhibition) of Na+/H+-exchange
2) Confidence 0.16 Published 1999 Journal Transplantation Section Title Doc Link 10589937 Disease Relevance 0.09 Pain Relevance 0.10
However, 3 other important health system cost variables would not show a significant decrease in simultaneous 2-team TKA: the percentage of patients requiring transfusion, mean number of transfused units of packed red blood cells, and percentage of patients going to an extended-care facility at discharge.
Negative_regulation (decrease) of TKA in red blood cells
3) Confidence 0.02 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2896355 Disease Relevance 0.06 Pain Relevance 0
On PL-Cox regression, the variables with positive coefficients were J-HAQ, VAS-pain, VAS-physician, and RF positive; advanced age was associated with a reduced risk of TKA.
Negative_regulation (reduced) of TKA associated with pain
4) Confidence 0.01 Published 2007 Journal Mod Rheumatol Section Abstract Doc Link 18084699 Disease Relevance 1.10 Pain Relevance 0.83
Age greater than 60 years was associated with a decreased risk of TKA, while J-HAQ from 0 to 1.5, VAS-pain >6 (cm), and VAS-physician >4 (cm) were associated with an increased risk for TKA surgery.
Negative_regulation (decreased) of TKA associated with pain
5) Confidence 0.01 Published 2007 Journal Mod Rheumatol Section Abstract Doc Link 18084699 Disease Relevance 0.97 Pain Relevance 0.78

General Comments

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