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Context Info
Confidence 0.03
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (FOS, Jund) nucleoplasm (FOS) aging (FOS)
nucleolus (FOS) DNA binding (Jund) protein complex (Jund)
Anatomy Link Frequency
striatum 1
FOS (Homo sapiens)
Jund (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 1 97.48 Very High Very High Very High
GABA receptor 1 97.16 Very High Very High Very High
nMDA receptor 1 96.88 Very High Very High Very High
GABAergic 1 90.20 High High
gABA 1 82.36 Quite High
Dopamine 1 77.92 Quite High
dopamine receptor 1 74.36 Quite High
agonist 1 67.88 Quite High
Disease Link Frequency Relevance Heat
Dyskinesias 7 99.30 Very High Very High Very High
Parkinson's Disease 3 85.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatments that caused dyskinesias induced, in the striatum, chronic Fos proteins of the deltaFosB family which, when coupled with Jun-D, form AP-1 complexes that can affect several genes, including enkephalin and N-methyl-D-aspartate receptor.
Fos Binding (coupled) of Jun-D in striatum associated with nmda receptor, enkephalin and dyskinesias
1) Confidence 0.03 Published 2000 Journal Ann. Neurol. Section Abstract Doc Link 10762134 Disease Relevance 0.77 Pain Relevance 0.39

General Comments

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