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Context Info
Confidence 0.43
First Reported 2000
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.05
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prkcc) plasma membrane (Prkcc) nucleus (Prkcc)
kinase activity (Prkcc) response to stress (Prkcc) cytoplasm (Prkcc)
Anatomy Link Frequency
neuronal 1
spinal cord dorsal horn 1
Prkcc (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 2 99.52 Very High Very High Very High
Dorsal horn 1 99.04 Very High Very High Very High
intrathecal 1 96.40 Very High Very High Very High
Neuropathic pain 1 89.80 High High
Peripheral nerve injury 3 85.52 High High
Morphine 2 75.00 Quite High
Hippocampus 2 75.00 Quite High
Central nervous system 1 64.92 Quite High
narcan 1 63.60 Quite High
antagonist 1 63.24 Quite High
Disease Link Frequency Relevance Heat
Injury 1 99.70 Very High Very High Very High
Hypersensitivity 2 98.72 Very High Very High Very High
Nervous System Injury 4 90.56 High High
Neuropathic Pain 1 89.80 High High
Nociception 4 75.88 Quite High
Targeted Disruption 1 75.00 Quite High
Cv Unclassified Under Development 1 52.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrated that MP can reduce OGD-induced neuronal injuries, and the down-regulation of cPKCgamma membrane translocation might be involved in the neuroprotection.
Regulation (regulation) of cPKCgamma in neuronal associated with injury
1) Confidence 0.43 Published 2008 Journal Neurosci. Lett. Section Abstract Doc Link 18706478 Disease Relevance 0.15 Pain Relevance 0.23
Conversely, chronic intrathecal delivery of exogenous galanin to nerve-intact adult rats is associated with persistent behavioural hypersensitivity, a significant increase in c-fos expression and an increase in PKCgamma immunoreactivity within the spinal cord dorsal horn.
Regulation (immunoreactivity) of PKCgamma in spinal cord dorsal horn associated with hypersensitivity, dorsal horn, spinal cord and intrathecal
2) Confidence 0.26 Published 2000 Journal Eur. J. Neurosci. Section Abstract Doc Link 10762308 Disease Relevance 0.90 Pain Relevance 0.49

General Comments

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