INT89465

Context Info Confidence 0.24 First Reported 2000 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 4 Total Number 4 Disease Relevance 1.03 Pain Relevance 0.41

endosome (Lhcgr) endoplasmic reticulum (Lhcgr) cytoplasm (Lhcgr) signal transducer activity (Lhcgr) extracellular space (Lhcgr) extracellular region (Lhcgr)

Lhcgr (Rattus norvegicus)

Pain Link Frequency Relevance Heat MU agonist 1 83.72 Opioid 2 78.72 anesthesia 2 70.88 agonist 4 52.48 antagonist 4 5.00 metalloproteinase 1 5.00 cINOD 1 5.00

Disease Link Frequency Relevance Heat Disease 2 99.98 Adrenocortical Hyperfunction 8 97.76 Targeted Disruption 6 79.60 Hyperplasia 2 77.52 Polycystic Ovary Syndrome 6 5.00 Diabetes Mellitus 1 5.00 Hyperandrogenism 1 5.00 Hyperinsulinism 1 5.00 Reprotox - General 3 1 5.00 Anovulation 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

FK stimulated LHR gene expression in SLCs and inhibited the gene expression in LLCs.

Positive_regulation (stimulated) of Gene_expression (expression) of LHR gene

1) Confidence 0.24 Published 2000 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 10898106 Disease Relevance 0 Pain Relevance 0.24

As expression of the LH receptor increases, the relative expression of PPAR?

Positive_regulation (increases) of Gene_expression (expression) of LH receptor

2) Confidence 0.08 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2795759 Disease Relevance 0.08 Pain Relevance 0.03

This condition may be defined as a disease resulting from the expression of LH-R on sex steroid-producing adrenocortical cells.

Positive_regulation (resulting) of Gene_expression (expression) of LH-R associated with disease

3) Confidence 0.04 Published 2002 Journal Mol. Cell. Endocrinol. Section Abstract Doc Link 12431804 Disease Relevance 0.47 Pain Relevance 0.07

This condition may be defined as a disease resulting from the expression of LH-R on sex steroid-producing adrenocortical cells.

Positive_regulation (resulting) of Gene_expression (expression) of LH-R associated with disease

4) Confidence 0.04 Published 2002 Journal Mol. Cell. Endocrinol. Section Abstract Doc Link 12431804 Disease Relevance 0.47 Pain Relevance 0.07

General Comments

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