INT9055

From wiki-pain
Revision as of 03:35, 21 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.68
First Reported 1989
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 22
Total Number 22
Disease Relevance 14.08
Pain Relevance 2.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cog1) Golgi apparatus (Cog1)
Anatomy Link Frequency
plasma 5
monocytes 1
coronary sinus 1
connective tissue 1
Cog1 (Mus musculus)
Pain Link Frequency Relevance Heat
Percutaneous transluminal coronary angioplasty 2 99.24 Very High Very High Very High
Angina 25 99.16 Very High Very High Very High
Versed 8 97.12 Very High Very High Very High
chemokine 7 95.40 Very High Very High Very High
Inflammatory response 41 87.72 High High
Inflammation 282 83.36 Quite High
transdermal 1 83.20 Quite High
endometriosis 4 82.56 Quite High
Pain 4 82.44 Quite High
agonist 6 75.00 Quite High
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 230 100.00 Very High Very High Very High
Hyperlipidemia 40 99.78 Very High Very High Very High
Stress 223 99.50 Very High Very High Very High
Spasticity 13 99.48 Very High Very High Very High
Cv General 3 Under Development 23 99.16 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

38 98.86 Very High Very High Very High
Coronary Artery Disease 46 98.72 Very High Very High Very High
Disease 162 98.24 Very High Very High Very High
Hypertriglyceridemia 11 97.96 Very High Very High Very High
Coronary Vasospasm 1 97.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Statistically significant increased levels of total cholesterol and low density lipoprotein cholesterol, as well as an increased low density lipoprotein cholesterol and high density lipoprotein cholesterol ratio were found for all groups with hereditary for hyperlipidemia (p less than 0.001).
Positive_regulation (increased) of low density lipoprotein associated with hyperlipidemia and disorder of lipid metabolism
1) Confidence 0.68 Published 1992 Journal Acta Paediatr. Section Abstract Doc Link 1606391 Disease Relevance 0.60 Pain Relevance 0.16
Statistically significant increased levels of total cholesterol and low density lipoprotein cholesterol, as well as an increased low density lipoprotein cholesterol and high density lipoprotein cholesterol ratio were found for all groups with hereditary for hyperlipidemia (p less than 0.001).
Positive_regulation (increased) of low density lipoprotein associated with hyperlipidemia and disorder of lipid metabolism
2) Confidence 0.68 Published 1992 Journal Acta Paediatr. Section Abstract Doc Link 1606391 Disease Relevance 0.60 Pain Relevance 0.16
Acute increases in plasma oxidized low-density lipoprotein immediately after percutaneous transluminal coronary angioplasty.
Positive_regulation (increases) of low-density lipoprotein in plasma associated with percutaneous transluminal coronary angioplasty
3) Confidence 0.58 Published 2001 Journal Am. J. Cardiol. Section Title Doc Link 11137843 Disease Relevance 0 Pain Relevance 0.13
Plasma oxidized low-density lipoprotein levels were significantly increased immediately after coronary angioplasty in patients with stable angina pectoris as well as in those with acute coronary syndromes.
Positive_regulation (increased) of low-density lipoprotein in Plasma associated with stable angina pectoris, acute coronary syndrome and angina
4) Confidence 0.58 Published 2001 Journal Am. J. Cardiol. Section Abstract Doc Link 11137843 Disease Relevance 0.19 Pain Relevance 0.13
Statistically significant increased levels of total cholesterol and low density lipoprotein cholesterol, as well as an increased low density lipoprotein cholesterol and high density lipoprotein cholesterol ratio were found for all groups with hereditary for hyperlipidemia (p less than 0.001).
Positive_regulation (increased) of low density lipoprotein associated with hyperlipidemia and disorder of lipid metabolism
5) Confidence 0.49 Published 1992 Journal Acta Paediatr. Section Abstract Doc Link 1606391 Disease Relevance 0.61 Pain Relevance 0.16
The plasma antioxidized low-density lipoprotein antibody levels (AcU/mL) in the coronary sinus increased in coronary spastic angina (38 +/- 16) compared with stable exertional angina (23 +/- 7) and control subjects (20 +/- 6) (p < or = 0.0001).
Positive_regulation (increased) of low-density in coronary sinus associated with angina and spasticity
6) Confidence 0.48 Published 2001 Journal Angiology Section Abstract Doc Link 11269779 Disease Relevance 1.46 Pain Relevance 0.82
In the propofol group, we observed a significant increase in triglycerides and very low-density lipoprotein levels 4 h postoperatively.
Positive_regulation (increase) of low-density lipoprotein
7) Confidence 0.40 Published 2007 Journal Yakugaku Zasshi Section Abstract Doc Link 17202798 Disease Relevance 0 Pain Relevance 0.25
BACKGROUND: Dyslipidemia with increased oxidative stress but without elevation of low-density lipoprotein cholesterol has been recently implicated in the pathogenesis of coronary vasospasm.
Neg (without) Positive_regulation (elevation) of low-density lipoprotein associated with stress and coronary vasospasm
8) Confidence 0.24 Published 2004 Journal Clin Cardiol Section Abstract Doc Link 15237693 Disease Relevance 0.27 Pain Relevance 0.07
There is ample evidence that hypercholesterolemia (that is, elevated plasma levels of low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL)) induced by genetic modification or enhanced intake of dietary lipids is a major causative factor in atherogenesis [2,3].
Positive_regulation (elevated) of low-density lipoprotein in plasma associated with atherosclerosis and hyperlipidemia
9) Confidence 0.14 Published 2007 Journal Genome Biol Section Body Doc Link PMC2375038 Disease Relevance 0.84 Pain Relevance 0.15
There is ample evidence that hypercholesterolemia (that is, elevated plasma levels of low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL)) induced by genetic modification or enhanced intake of dietary lipids is a major causative factor in atherogenesis [2,3].
Positive_regulation (elevated) of low-density lipoprotein in plasma associated with atherosclerosis and hyperlipidemia
10) Confidence 0.14 Published 2007 Journal Genome Biol Section Body Doc Link PMC2375038 Disease Relevance 0.82 Pain Relevance 0.14
Due to this sequestration, the subsequent induction of all low-density lipoprotein cholesterol-mediated homeostatic responses (more specially cholesteryl ester formation) is retarded in Niemann-Pick C disease cells.
Positive_regulation (induction) of low-density lipoprotein associated with disease
11) Confidence 0.12 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2902432 Disease Relevance 0.42 Pain Relevance 0
There is convincing evidence from epidemiological and intervention studies that elevated low-density lipoprotein, reduced high-density lipoprotein cholesterol and elevated triglycerides in plasma are positively correlated to the progression of atherosclerosis and CVD

[Assmann et al., 1998; Sprecher, 1998].

Positive_regulation (elevated) of low-density lipoprotein in plasma associated with hypertriglyceridemia, cardiovascular disease and atherosclerosis
12) Confidence 0.09 Published 2003 Journal Nuclear Receptor Signaling Section Body Doc Link PMC1402228 Disease Relevance 1.48 Pain Relevance 0.20
High levels of low-density lipoprotein cholesterol are reduced and, where low at baseline, high-density lipoprotein levels are increased.
Positive_regulation (increased) of low-density lipoprotein
13) Confidence 0.07 Published 1989 Journal Cardiology Section Abstract Doc Link 2653620 Disease Relevance 0.72 Pain Relevance 0.07
This in vivo approach resulted in reduction of the elevated intermediate density lipoprotein (IDL)/LDL ratio to normal levels, four days after vector delivery [129].
Positive_regulation (elevated) of intermediate density lipoprotein associated with disorder of lipid metabolism
14) Confidence 0.06 Published 2010 Journal Int Arch Med Section Body Doc Link PMC3016243 Disease Relevance 0.62 Pain Relevance 0
The Cs-Ao difference of malondialdehyde-modified low-density lipoprotein (MDA-LDL) level, as a marker of atherothrombosis, in focal vasospasm increased significantly as compared with diffuse vasospasm (6.9+/-6.7 vs. 1.2+/-5.7 U/L, p=0.001).
Positive_regulation (increased) of low-density lipoprotein
15) Confidence 0.05 Published 2009 Journal Int. J. Cardiol. Section Body Doc Link 18614250 Disease Relevance 0.38 Pain Relevance 0
At the cellular and molecular levels, our results are supported by the fact that insulin has demonstrated proliferative effects on cultured vascular smooth muscle cells; it also enhances lipid synthesis and low density lipoprotein binding to these cells as well as connective tissue synthesis in arterial wall (Stout 1992; Bouguerra et al 2001).
Positive_regulation (enhances) of low density lipoprotein in connective tissue
16) Confidence 0.05 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994018 Disease Relevance 1.41 Pain Relevance 0.07
Mean serum high density lipoprotein-cholesterol levels are increased and low density lipoprotein-cholesterol levels are decreased during treatment with oral estradiol plus sequential dydrogesterone.
Positive_regulation (increased) of low density lipoprotein-cholesterol
17) Confidence 0.04 Published 1997 Journal Drugs Aging Section Abstract Doc Link 9342560 Disease Relevance 0.62 Pain Relevance 0.12
A reversible decrease in high density lipoprotein-cholesterol and increase in low density lipoprotein:high density lipoprotein ratio was noted only in the patients receiving combination therapy, but not in those receiving GnRHa only.
Positive_regulation (increase) of low density lipoprotein
18) Confidence 0.04 Published 1992 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1386374 Disease Relevance 0.27 Pain Relevance 0.25
The first in vitro characterizations of putative EPCs were done by uptake of acetylated low density lipoprotein and Ulex europaeus lectin binding and these capabilities were shown to be shared by monocytes.
Positive_regulation (acetylated) of low density lipoprotein in monocytes
19) Confidence 0.03 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721378 Disease Relevance 0 Pain Relevance 0.05
Level of low-density lipoprotein (LDL) cholesterol typically is not elevated and in fact may even be below average.
Neg (not) Positive_regulation (elevated) of low-density lipoprotein
20) Confidence 0.02 Published 2010 Journal Int Arch Med Section Body Doc Link PMC3002890 Disease Relevance 1.35 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox