INT90561

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Context Info
Confidence 0.02
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.25
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Abat) transport (Slc6a1) plasma membrane (Slc6a1)
Anatomy Link Frequency
thalamus 1
hippocampus 1
Slc6a1 (Mus musculus)
Abat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 20 100.00 Very High Very High Very High
Hippocampus 6 93.80 High High
Thalamus 8 93.16 High High
anticonvulsant 6 85.52 High High
halothane 2 51.92 Quite High
anesthesia 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Epilepsy 4 66.56 Quite High
Convulsion 8 59.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study examines the effect of tiagabine (a selective inhibitor of GABA transporter 1, GAT-1), SNAP-5114 (a semi-selective inhibitor of rat GAT-3/mouse GAT4) and NNC 05-2045 (a non-selective GABA uptake inhibitor) in modulating GABA levels in the hippocampus and thalamus.
GAT-1 Negative_regulation (inhibitor) of GABA in hippocampus associated with gaba, thalamus and hippocampus
1) Confidence 0.02 Published 2000 Journal Neuropharmacology Section Abstract Doc Link 10974324 Disease Relevance 0.13 Pain Relevance 0.46
The present study examines the effect of tiagabine (a selective inhibitor of GABA transporter 1, GAT-1), SNAP-5114 (a semi-selective inhibitor of rat GAT-3/mouse GAT4) and NNC 05-2045 (a non-selective GABA uptake inhibitor) in modulating GABA levels in the hippocampus and thalamus.
GAT-1 Negative_regulation (inhibitor) of GABA in thalamus associated with gaba, thalamus and hippocampus
2) Confidence 0.01 Published 2000 Journal Neuropharmacology Section Abstract Doc Link 10974324 Disease Relevance 0.13 Pain Relevance 0.46

General Comments

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