INT90740

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Context Info
Confidence 0.23
First Reported 1999
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 1.43
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (Cacna1a) plasma membrane (Cacna1a) nucleus (Cacna1a)
neurological system process (Cacna1a) transmembrane transport (Cacna1a) cytoplasm (Cacna1a)
Cacna1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Migraine 17 100.00 Very High Very High Very High
corticosteroid 35 85.12 High High
Glutamate 2 57.68 Quite High
tolerance 3 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Migraine With Aura 11 100.00 Very High Very High Very High
Migraine Without Aura 3 99.28 Very High Very High Very High
Ataxia 1 92.04 High High
Spinocerebellar Ataxia Type 2 1 89.60 High High
Headache 3 89.08 High High
Exsanguination 2 5.00 Very Low Very Low Very Low
Insulin Resistance 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Functional Bowel Disorder 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Absence of known familial hemiplegic migraine (FHM) mutations in the CACNA1A gene in patients with common migraine: implications for genetic testing.
Negative_regulation (Absence) of CACNA1A gene associated with migraine with aura, migraine and migraine without aura
1) Confidence 0.23 Published 2003 Journal Clin. Chem. Lab. Med. Section Title Doc Link 12705332 Disease Relevance 0.93 Pain Relevance 0.93
Detection of a novel missense mutation and second recurrent mutation in the CACNA1A gene in individuals with EA-2 and FHM.
Negative_regulation (Detection) of CACNA1A
2) Confidence 0.18 Published 1999 Journal Hum. Genet. Section Title Doc Link 10987655 Disease Relevance 0.50 Pain Relevance 0.31
Arginase and GDH seemed to show saturability in stimulation by the biosignal similar to a few of Class 1 genes.
Negative_regulation (few) of Class
3) Confidence 0.03 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0.14

General Comments

This test has worked.

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