INT90831

Context Info Confidence 0.40 First Reported 2000 Last Reported 2000 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.39 Pain Relevance 0.58

transmembrane transporter activity (SLC22A6) plasma membrane (SLC22A6) protein complex (SLC22A6) transmembrane transport (SLC22A6)

SLC22A6 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 7 99.70

Disease Link Frequency Relevance Heat INFLAMMATION 2 83.00 Nephrotoxicity 2 61.36 Acquired Immune Deficiency Syndrome Or Hiv Infection 4 58.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Importantly, NSAIDs significantly reduced the shift in adefovir cytotoxicity observed upon hOAT1 expression with ketoprofen and naproxen being 2- to 3-times more effective than probenecid.

Negative_regulation (reduced) of Gene_expression (expression) of hOAT1 associated with cinod

1) Confidence 0.40 Published 2000 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10991954 Disease Relevance 0.39 Pain Relevance 0.58

General Comments

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