INT92243

Context Info Confidence 0.31 First Reported 2000 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 4 Disease Relevance 1.79 Pain Relevance 0.19

extracellular region (F13a1) transferase activity, transferring acyl groups (F13a1) cytoplasm (F13a1)

Anatomy Link Frequency plasma 2 platelets 1 F13a1 (Mus musculus)

Pain Link Frequency Relevance Heat cva 3 97.28 Pain 1 90.68 Restless leg syndrome 8 50.00 headache 3 25.00

Disease Link Frequency Relevance Heat Anaemia 1 100.00 Chronic Subdural Hematoma 5 99.16 Renal Failure 1 98.64 Cv General 3 Under Development 2 97.28 Hemorrhage 1 95.56 Hematuria 1 94.32 Hematoma 1 93.76 Pain 1 90.68 Injury 1 86.68 Rupture 1 84.04

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The authors report on three young men with a deficiency in coagulation factor XIII (FXIII) who underwent surgery for chronic SDHs.

factor XIII Binding (underwent) of associated with chronic subdural hematoma

1) Confidence 0.31 Published 2005 Journal J. Neurosurg. Section Abstract Doc Link 16028774 Disease Relevance 0.77 Pain Relevance 0.05

Hematological tests show: mild anemia with leucocytosis; prolonged PT, PTT and ThT; decreased fibrinogen, factor V, factor XIII, plasminogen and alpha2-antiplasmin levels; increased factor VIII:c, von Willebrand factor, and FDPs/D-dimers levels with normal ATIII and platelets.

factor XIII Binding (anemia) of in platelets associated with anaemia

2) Confidence 0.03 Published 2000 Journal Biochimie Section Abstract Doc Link 11086223 Disease Relevance 0.73 Pain Relevance 0.14

Ex vivo assays for fibrin clot permeation, fiber thickness, factor XIII cross-linking activity, and fibrinolysis were performed on the plasma of the above subjects.

factor XIII Binding (linking) of in plasma

3) Confidence 0.02 Published 2008 Journal J. Vasc. Surg. Section Body Doc Link 18829228 Disease Relevance 0.14 Pain Relevance 0

Ex vivo assays for fibrin clot permeation, fiber thickness, factor XIII cross-linking activity, and fibrinolysis were performed on the plasma of the above subjects.

factor XIII Binding (cross) of in plasma

4) Confidence 0.02 Published 2008 Journal J. Vasc. Surg. Section Body Doc Link 18829228 Disease Relevance 0.14 Pain Relevance 0

General Comments

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