INT93007

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Context Info
Confidence 0.41
First Reported 2000
Last Reported 2011
Negated 1
Speculated 3
Reported most in Body
Documents 7
Total Number 10
Disease Relevance 3.47
Pain Relevance 6.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
DMEC 8
leucocyte 2
CALM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
complementary and alternative medicine 478 100.00 Very High Very High Very High
substance P 24 100.00 Very High Very High Very High
Neuropeptide 9 100.00 Very High Very High Very High
cytokine 8 99.84 Very High Very High Very High
Opioid 54 99.80 Very High Very High Very High
Inflammation 48 99.28 Very High Very High Very High
Inflammatory response 8 97.76 Very High Very High Very High
palliative 3 97.76 Very High Very High Very High
chronic pain syndrome 2 96.08 Very High Very High Very High
cocaine 10 93.60 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 52 99.28 Very High Very High Very High
Tonsillar Neoplasms 1 97.12 Very High Very High Very High
Complex Regional Pain Syndromes 2 96.08 Very High Very High Very High
Adhesions 23 93.04 High High
Low Back Pain 18 91.60 High High
Pain 105 90.12 High High
Diabetes Mellitus 59 87.76 High High
Cancer 104 86.64 High High
Spinal Cord Injury 2 74.84 Quite High
Stress 9 71.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We then determined the in vivo effect of released neuropeptides on DMEC CAM expression.
Spec (determined) Regulation (effect) of Gene_expression (expression) of CAM in DMEC associated with neuropeptide
1) Confidence 0.41 Published 2000 Journal J. Investig. Dermatol. Symp. Proc. Section Abstract Doc Link 11147679 Disease Relevance 0.48 Pain Relevance 0.64
The third section of the survey, based on a review of Taiwanese and English language literature, focused on patterns of CAM use including: the reasons for CAM use, factors influencing the decision to use CAM, the administration of CAM with conventional treatments, the disclosure of CAM use to healthcare professionals, and the reasons for not using CAM or ceasing CAM.
Regulation (reasons) of Gene_expression (use) of CAM
2) Confidence 0.39 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952338 Disease Relevance 0.16 Pain Relevance 0
Theme 2: Types of evidence: patients' criteria for evaluating CAM information and therapies
Regulation (evaluating) of Gene_expression (information) of CAM associated with complementary and alternative medicine
3) Confidence 0.39 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC2000907 Disease Relevance 0.25 Pain Relevance 0.57
, Has your attitude towards CAM changed/not changed throughout your degree and if so why?"
Neg (not) Regulation (changed) of Gene_expression (attitude) of CAM associated with complementary and alternative medicine
4) Confidence 0.39 Published 2008 Journal BMC Complement Altern Med Section Body Doc Link PMC2267156 Disease Relevance 0 Pain Relevance 0.40
In recent studies, our laboratory examined the direct effect of SP on DMEC CAM expression and function in vitro and in vivo.
Spec (examined) Regulation (effect) of Gene_expression (expression) of CAM in DMEC associated with substance p
5) Confidence 0.30 Published 2000 Journal J. Investig. Dermatol. Symp. Proc. Section Abstract Doc Link 11147679 Disease Relevance 0.52 Pain Relevance 0.52
What is the role of CAM therapy in patients receiving opioids?
Regulation (role) of Gene_expression (therapy) of CAM associated with complementary and alternative medicine and opioid
6) Confidence 0.29 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC1885447 Disease Relevance 0.48 Pain Relevance 1.45
What are reasonable outcomes to expect from CAM therapy and opioids?
Regulation (expect) of Gene_expression (therapy) of CAM associated with complementary and alternative medicine and opioid
7) Confidence 0.29 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC1885447 Disease Relevance 0.53 Pain Relevance 1.57
Little is known regarding the cellular regulatory events by which SP modulates DMEC CAM expression.
Regulation (modulates) of Gene_expression (expression) of CAM in DMEC associated with substance p
8) Confidence 0.26 Published 2000 Journal J. Investig. Dermatol. Symp. Proc. Section Abstract Doc Link 11147679 Disease Relevance 0.41 Pain Relevance 0.65
CAM surface expression by endothelial cells is regulated by cytokines and inflammatory activators.31 32 Previously, we have shown that the CAM expression in HIMECs was enhanced in response to dual inflammatory stimulation with TNF?
Regulation (regulated) of Gene_expression (expression) of CAM in endothelial cells associated with inflammation and cytokine
9) Confidence 0.14 Published 2008 Journal Gut Section Body Doc Link PMC2582343 Disease Relevance 0.24 Pain Relevance 0.15
/LPS.28 29 Here, we examined the effect of curcumin pretreatment on CAM expression and leucocyte binding in HIMECs following TNF?
Spec (examined) Regulation (effect) of Gene_expression (expression) of CAM in leucocyte
10) Confidence 0.09 Published 2008 Journal Gut Section Body Doc Link PMC2582343 Disease Relevance 0.40 Pain Relevance 0.14

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