INT93635
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
This stimulation was due to soluble factors released from the chromaffin cells under basal, unstimulated conditions and involved the increased expression of P450 enzymes, StAR and de novo protein synthesis. | |||||||||||||||
| |||||||||||||||
|
When the gene expression of the P450 enzymes synthesizing these epoxides were looked at, the data were found to be consistent with EET levels, indicating differences in the mediators other than EETs in the mechanism of the end organ injury. | |||||||||||||||
| |||||||||||||||
|
The nitric oxide (NO) donor, O(2)-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO), is metabolized by P450 enzymes to release NO in the liver and possibly other tissues. | |||||||||||||||
| |||||||||||||||
|
This stimulation was due to soluble factors released from the chromaffin cells under basal, unstimulated conditions and involved the increased expression of P450 enzymes, StAR and de novo protein synthesis. | |||||||||||||||
| |||||||||||||||
|
Other examples of cross-talks between RXR's partners include PPAR with COUP-TF [52], TR with LXR [53], TR with VDR [54], and multiple partners (CAR, PXR, LXR, FXR, and PPAR) on the expression of P450 enzymes [55].
3.2. | |||||||||||||||
| |||||||||||||||
|
When the gene expression of the P450 enzymes synthesizing these epoxides were looked at, the data were found to be consistent with EET levels, indicating differences in the mediators other than EETs in the mechanism of the end organ injury. | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.