INT94014

Context Info Confidence 0.36 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.16

extracellular space (EDN1, EDN3) extracellular region (EDN1, EDN3) cell-cell signaling (EDN1, EDN3) signal transduction (EDN3) cytoplasm (EDN1)

EDN1 (Homo sapiens) EDN3 (Homo sapiens)

Pain Link Frequency Relevance Heat antagonist 2 86.96 tetrodotoxin 1 76.12

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

One class (ET(A) receptor) had a high affinity for ET-1 and ET-2 but a low affinity for ET-3, and the other (ET(B) receptor) a high affinity for ET-1, ET-2 and ET-3.

Positive_regulation (affinity) of ET-1 Binding (affinity) of ET-3

1) Confidence 0.36 Published 2001 Journal Regul. Pept. Section Abstract Doc Link 11231044 Disease Relevance 0 Pain Relevance 0.16

General Comments

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