INT94262

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Context Info
Confidence 0.22
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) plasma membrane (PTGER2)
IL1B (Homo sapiens)
PTGER2 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 3 98.80 Very High Very High Very High
cytokine 3 81.20 Quite High
cINOD 3 77.60 Quite High
COX2 2 76.08 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 2 90.76 High High
Necrosis 1 85.52 High High
Cancer 1 85.16 High High
Disease 6 82.84 Quite High
INFLAMMATION 1 72.32 Quite High
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
COX inhibitors indomethacin and BF389, as well as the glucocorticoid dexamethasone (DEX) and pyrrolidinedithiocarbamate, which is an inhibitor of nuclear factor kappaB as well as a potent antioxidant, inhibited IL-1beta induced PGE2 secretion.
IL-1beta Positive_regulation (induced) of Localization (secretion) of PGE2 associated with dexamethasone
1) Confidence 0.22 Published 2001 Journal Exp. Gerontol. Section Abstract Doc Link 11250126 Disease Relevance 0.80 Pain Relevance 0.49

General Comments

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