INT94270

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Context Info
Confidence 0.17
First Reported 2001
Last Reported 2001
Negated 2
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.67
Pain Relevance 1.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pomc, Crh) extracellular space (Pomc, Crh) extracellular region (Pomc, Crh)
response to stress (Crh) cell-cell signaling (Pomc) generation of precursor metabolites and energy (Pomc)
Anatomy Link Frequency
nucleus 4
Pomc (Rattus norvegicus)
Crh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 12 99.92 Very High Very High Very High
Opioid 4 95.20 Very High Very High Very High
Intracerebroventricular 4 91.76 High High
opioid receptor 4 67.24 Quite High
Central nervous system 2 64.00 Quite High
Arthritis 6 59.28 Quite High
Inflammation 2 29.28 Quite Low
Disease Link Frequency Relevance Heat
Stress 12 91.84 High High
Arthritis 6 59.28 Quite High
INFLAMMATION 2 29.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Corticotrophin-releasing factor (CRF) mRNA and arginine vasopressin (AVP) mRNA in the paraventricular nucleus (PVN) and POMC mRNA in the anterior pituitary were found to be unaffected by either morphine or endomorphins.
POMC mRNA Neg (unaffected) Regulation (unaffected) of Transcription (mRNA) of CRF in nucleus associated with morphine
1) Confidence 0.17 Published 2001 Journal J. Endocrinol. Section Abstract Doc Link 11250660 Disease Relevance 0.34 Pain Relevance 0.79
Corticotrophin-releasing factor (CRF) mRNA and arginine vasopressin (AVP) mRNA in the paraventricular nucleus (PVN) and POMC mRNA in the anterior pituitary were found to be unaffected by either morphine or endomorphins.
POMC mRNA Neg (unaffected) Regulation (unaffected) of Transcription (mRNA) of Corticotrophin-releasing factor in nucleus associated with morphine
2) Confidence 0.17 Published 2001 Journal J. Endocrinol. Section Abstract Doc Link 11250660 Disease Relevance 0.34 Pain Relevance 0.80

General Comments

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