INT94537

Context Info Confidence 0.11 First Reported 2001 Last Reported 2001 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 1.29 Pain Relevance 0.14

Anatomy Link Frequency bladder 2 Metallothionein isoform 1 (Homo sapiens)

Pain Link Frequency Relevance Heat interstitial cystitis 2 76.84

Disease Link Frequency Relevance Heat Bladder Cancer 18 98.60 Bladder Disease 2 78.44 Cystitis 2 77.36 Interstitial Cystitis 2 76.84 Carcinoma In Situ 2 72.32 Cancer 4 63.80

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Metallothionein isoform 1 and 2 gene expression in the human bladder: evidence for upregulation of MT-1X mRNA in bladder cancer.

Gene_expression (expression) of Metallothionein isoform 1 in bladder associated with bladder cancer

1) Confidence 0.11 Published 2001 Journal Cancer Detect. Prev. Section Title Doc Link 11270423 Disease Relevance 0.75 Pain Relevance 0.08

The goals of this study were to determine the expression of metallothionein isoform 1 and 2 proteins (MT-1 and MT-2) in bladder cancer and then to determine which MT isoform-specific genes promoted the expression of these proteins.

Spec (determine) Gene_expression (expression) of metallothionein isoform 1 in bladder associated with bladder cancer

2) Confidence 0.11 Published 2001 Journal Cancer Detect. Prev. Section Abstract Doc Link 11270423 Disease Relevance 0.54 Pain Relevance 0.07

General Comments

This test has worked.