INT96887

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Context Info
Confidence 0.45
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP1B1) endoplasmic reticulum (CYP1B1)
Anatomy Link Frequency
endometrium 2
CYP1B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 4 98.28 Very High Very High Very High
pain pelvic 1 73.92 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis (extended) 4 98.28 Very High Very High Very High
Disease 15 97.00 Very High Very High Very High
Glaucoma 48 95.04 Very High Very High Very High
Reprotox - General 3 1 73.92 Quite High
Ocular Hypertension 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Hydrophthalmos 2 5.00 Very Low Very Low Very Low
Corneal Edema 1 5.00 Very Low Very Low Very Low
Aniridia 1 5.00 Very Low Very Low Very Low
Blindness 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, both affected individuals were homozygous in the CYP1B1 region, making it likely that a mutation in the promoter or in some other regulatory region of the gene is responsible for the disease.
Regulation (homozygous) of Gene_expression (region) of CYP1B1 associated with disease
1) Confidence 0.45 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2709423 Disease Relevance 0.49 Pain Relevance 0
Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium.
Regulation (Effect) of Gene_expression (expression) of CYP1B1 in endometrium
2) Confidence 0.45 Published 2001 Journal Toxicol. Sci. Section Title Doc Link 11452143 Disease Relevance 0.42 Pain Relevance 0.20

General Comments

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