INT97565

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Context Info
Confidence 0.45
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (JUN) transport (ABCB1) nuclear chromosome (JUN)
aging (JUN) DNA binding (JUN) transmembrane transport (ABCB1)
JUN (Homo sapiens)
ABCB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 1 10.00 Low Low
cINOD 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 2 63.04 Quite High
Cancer 3 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesized that increased prostaglandin production by Cox-2 induces PKC and the expression of transcriptional factor c-Jun, which in turn, induces the expression of MDR1/Pgp170.
c-Jun Positive_regulation (induces) of Gene_expression (expression) of MDR1
1) Confidence 0.45 Published 2001 Journal Anticancer Res. Section Body Doc Link 11501838 Disease Relevance 0.06 Pain Relevance 0

General Comments

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