INT97664

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Context Info
Confidence 0.48
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (AKR1C2) cytoplasm (AKR1C2)
AKR1C2 (Homo sapiens)
Pain Link Frequency Relevance Heat
fluoxetine 2 95.68 Very High Very High Very High
Central nervous system 2 93.88 High High
Bile 6 88.84 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The carboxylate of ursodeoxycholate binds to AKR1C2 in the oxyanion hole at the active site.
AKR1C2 Binding (binds) of
1) Confidence 0.48 Published 2001 Journal Biochemistry Section Abstract Doc Link 11513593 Disease Relevance 0 Pain Relevance 0.25
Like other members of the superfamily, AKR1C2 folds into an alpha/beta-barrel and binds NADP(+) in an extended conformation.
AKR1C2 Binding (binds) of
2) Confidence 0.48 Published 2001 Journal Biochemistry Section Abstract Doc Link 11513593 Disease Relevance 0 Pain Relevance 0.26

General Comments

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