INT98660

Context Info Confidence 0.45 First Reported 2001 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.67 Pain Relevance 0.62

intracellular (SGSM3) cell cycle (SGSM3) cytoplasm (SGSM3)

SGSM3 (Homo sapiens)

Pain Link Frequency Relevance Heat cva 136 99.60 Opioid 2 80.76 Neuropeptide 1 78.60 orphanin 1 28.64 Enkephalin 2 27.36 cerebral cortex 4 5.00 epidural 2 5.00 agonist 2 5.00 anesthesia 1 5.00 ischemia 1 5.00

Disease Link Frequency Relevance Heat Cv General 3 Under Development 133 99.60 Hypoxia 2 93.24 Soft Tissue Injuries 2 84.88 Stress 6 77.84 Death 4 74.64 Contusions 1 74.24 Neurodegenerative Disease 1 71.52 Brain Injury 27 70.24 Stroke 1 69.20 Head Trauma 5 66.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Western blot analysis and immunocytochemistry revealed that H2O2 treatment elicited the phosphorylation and nuclear translocation of ERK 1/2 and p38 MAP kinases.

Positive_regulation (elicited) of Localization (translocation) of MAP

1) Confidence 0.45 Published 2001 Journal J. Neurochem. Section Abstract Doc Link 11595755 Disease Relevance 0.52 Pain Relevance 0.20

When there is no relationship between MAP and ICP, increasing MAP typically will not increase ICP [15,22,23] Thus, when the CAP Index is increased and ICP cannot be reduced, increasing MAP may improve CPP.

Positive_regulation (increasing) of Localization (improve) of MAP associated with cva

2) Confidence 0.05 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.15 Pain Relevance 0.42

General Comments

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