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Context Info
Confidence 0.59
First Reported 2001
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.43
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ctnnb1) enzyme binding (Ctnnb1) DNA binding (Ctnnb1)
protein complex (Ctnnb1) cytoplasm (Ctnnb1) cell proliferation (Ctnnb1)
Ctnnb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 1 82.80 Quite High
cINOD 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Colorectal Cancer 5 99.56 Very High Very High Very High
INFLAMMATION 5 96.32 Very High Very High Very High
Cancer 5 91.32 High High
Apoptosis 2 89.40 High High
Colon Cancer 1 80.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of beta-catenin translocation in rodent colorectal tumors: a novel explanation for the protective effect of nonsteroidal antiinflammatory drugs in colorectal cancer.
Negative_regulation (Inhibition) of Localization (translocation) of beta-catenin associated with colorectal cancer and inflammation
1) Confidence 0.59 Published 2001 Journal Dig. Dis. Sci. Section Title Doc Link 11713928 Disease Relevance 1.19 Pain Relevance 0.06
However, in the azoxymethane-treated rat, where beta-catenin is frequently rendered GSK-3beta-insensitive, nabumetone failed to alter beta-catenin levels but did decrease beta-catenin nuclear localization and transcriptional activity as gauged by cyclin D1.
Neg (failed) Negative_regulation (decrease) of Localization (localization) of beta-catenin
2) Confidence 0.33 Published 2005 Journal Cancer Lett. Section Abstract Doc Link 15617833 Disease Relevance 0.24 Pain Relevance 0.12

General Comments

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